CIR1

Gene Symbol CIR1
Entrez Gene 9541
Alt Symbol CIR
Species Human
Gene Type protein-coding
Description corepressor interacting with RBPJ, 1
Other Description CBF1 interacting corepressor|CBF1-interacting corepressor|corepressor interacting with RBPJ 1|recepin
Swissprots A8K8M4 Q8IWI2 Q86X95 Q4G1B9 Q12804 A6NFI6 Q6PJI4 O95367
Accessions AAY24216 EAX11144 EAX11145 EAX11146 Q86X95 AF098297 AAD05243 AK292389 BAF85078 BC015040 BC021175 AAH21175 BC031018 AAH31018 BC038987 AAH38987 BC046098 AAH46098 BU596189 U03644 AAA17853 NM_199075 NM_004882 NP_004873
Function May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription. {ECO:0000250, ECO:0000269|PubMed:19409814, ECO:0000269|PubMed:9874765}.
Subcellular Location Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome.
Tissue Specificity Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas. {ECO:0000269|PubMed:9874765}.
Top Pathways Notch signaling pathway

CIR CRISPR/Cas9 KO Plasmid (h) - sc-408800 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR HDR Plasmid (h) - sc-408800-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR Double Nickase Plasmid (h) - sc-408800-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR Double Nickase Plasmid (h2) - sc-408800-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR CRISPR Activation Plasmid (h) - sc-408800-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR CRISPR Activation Plasmid (h2) - sc-408800-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR Lentiviral Activation Particles (h) - sc-408800-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR Lentiviral Activation Particles (h2) - sc-408800-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CIR siRNA (h) - sc-38213 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CIR shRNA Plasmid (h) - sc-38213-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CIR shRNA (h) Lentiviral Particles - sc-38213-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU082111 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6137 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6137 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CIR1 siRNA (Human) - CRH6345 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBF1-interacting corepressor RNAi - H00009541-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CIR1 - MBS8237546 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CIR1 (NM_004882.3) - SHH264145 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CIR(NM_004882.3) - SHG169921 from Creative biogene

Category siRNA
Species Reactivities Human

Human CIR1 siRNA - orb266847 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CIR1 shRNA Plasmid (Human) - CHH6345 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CIR1 miRNA 3'UTR clone - MiUTR1H-02170 from Creative biogene

Species Reactivities Human
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