ALKBH7

Gene Symbol ALKBH7
Entrez Gene 84266
Alt Symbol ABH7, SPATA11, UNQ6002
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 7 (E. coli)
Other Description alkylated DNA repair protein alkB homolog 7|alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial|probable alpha-ketoglutarate-dependent dioxygenase ABH7|spermatogenesis associated 11|spermatogenesis cell proliferation related protein|spermatogenesis cell proliferation-related protein|spermatogenesis-associated protein 11
Swissprots Q9BT30 B2R4U9 Q53FF3
Accessions EAW69102 Q9BT30 AK223336 BAD97056 AK311956 BAG34896 AY358858 AAQ89217 AY427650 AAR24624 BC004393 AAH04393 BM271861 BX334356 XM_005259658 XP_005259715 NM_032306 NP_115682
Function May function as protein hydroxylase; can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism (By similarity). {ECO:0000250|UniProtKB:Q9D6Z0, ECO:0000269|PubMed:23666923, ECO:0000269|PubMed:25122757}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:23666923}.
Tissue Specificity Widely expressed, with highest expression in pancreas, followed by spleen, prostate, ovary and placenta. {ECO:0000269|PubMed:17979886}.

ALKBH7 (D-19) - sc-244895 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ALKBH7 (S-18) - sc-244894 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ALKBH7 (Y-19) - sc-244893 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ALKBH7 antibody - ab122596 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122596, at 1/20 dilution, staining ALKBH7 in paraffin embedded Human pancreas by Immunohistochemistry.

Anti-ALKBH7 Antibody - LS-C335223 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

ALKBH7 Antibody - NBP2-38450 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ALKBH7 Antibody [NBP2-38450] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative Control. Lane 3: Overexpression lysate

ALKBH7 Antibody - NBP1-81231 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ALKBH7 antibody produced in rabbit - HPA039872 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ALKBH7: <B>Cat. No. HPA039872</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-ALKBH7 (181-195) antibody produced in rabbit - SAB1102788 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human ALKBH7 was separated on SDS-PAGE, blotted with Anti-ALKBH7 (181-195) (<B>Cat. No. SAB1102788</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:500 + ALKBH7 immunizing peptide (human, 181-195)

Anti -ALKBH7 (Alkylated DNA Repair Protein alkB Homolog 7, ABH7, SPATA11, UNQ6002) - 209490 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

ALKBH7 Polyclonal Antibody - A2331 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse eye cells, using ALKBH7 antibody.

ALKBH7 antibody - 70R-15685 from Fitzgerald

Host Rabbit
Clonality Polyclonal

ALKBH7 Antibody - abx001893 from Abbexa

Host Rabbit
Clonality Polyclonal

ALKBH7 / SPATA11 antibody - 15470-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human testis were subjected to SDS PAGE followed by western blot with 15470-1-AP(ALKBH7 Antibody) at dilution of 1:500

Anti-ALKBH7, Polyclonal Antibody - 25-A2331 from ARP American Research Products

Prices $299.00, $449.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

ALKBH7 antibody - 15470-1-AP from Proteintech Group

Prices $279.00
Sizes con: 20 μg/150μl
Host Rabbit
Clonality Polyclonal
human testis tissue were subjected to SDS PAGE followed by western blot with 15470-1-AP(ALKBH7 antibody) at dilution of 1:500

Anti-ALKBH7 antibody - STJ22590 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

ALKBH7 - A2331 from NeoScientific

Prices $220.00, $380.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

alkB, alkylation repair homolog 7, Polyclonal Antibody - MBS711214 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

ALKBH7, Polyclonal Antibody - MBS2517505 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

ALKBH7 , Polyclonal Antibody - MBS126308 from MyBioSource

Prices $230.00, $305.00, $460.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

ALKBH7 Antibody - EPP10336 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
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Anti-ALKBH7 (aa 100-188) polyclonal antibody - DPABH-20900 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-ALKBH7 monoclonal antibody - DCABH-200157 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

ALKBH7 Antibody - 15093 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from U266, K-562, and Raji cells using ALKBH7 Antibody.
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