ALKBH7

Gene Symbol ALKBH7
Entrez Gene 84266
Alt Symbol ABH7, SPATA11, UNQ6002
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 7 (E. coli)
Other Description alkylated DNA repair protein alkB homolog 7|alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial|probable alpha-ketoglutarate-dependent dioxygenase ABH7|spermatogenesis associated 11|spermatogenesis cell proliferation related protein|spermatogenesis cell proliferation-related protein|spermatogenesis-associated protein 11
Swissprots Q9BT30 B2R4U9 Q53FF3
Accessions EAW69102 Q9BT30 AK223336 BAD97056 AK311956 BAG34896 AY358858 AAQ89217 AY427650 AAR24624 BC004393 AAH04393 BM271861 BX334356 XM_005259658 XP_005259715 NM_032306 NP_115682
Function May function as protein hydroxylase; can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism (By similarity). {ECO:0000250|UniProtKB:Q9D6Z0, ECO:0000269|PubMed:23666923, ECO:0000269|PubMed:25122757}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:23666923}.
Tissue Specificity Widely expressed, with highest expression in pancreas, followed by spleen, prostate, ovary and placenta. {ECO:0000269|PubMed:17979886}.

Probable alpha-ketoglutarate-dependent dioxygenase ABH7 (ALKBH7), Human, ELISA Kit - CSB-EL001613HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

alkB, alkylation repair homolog 7 (E. coli) , ELISA Kit - MBS913875 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human ALKBH7 is typically less than 5.86 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 23.44 pg/ml -1500 pg/ml.

Probable alpha-ketoglutarate-dependent dioxygenase ABH7, ELISA Kit - MBS282499 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Probable alpha-ketoglutarate-dependent dioxygenase ABH7(ALKBH7) ELISA kit - CSB-EL001613HU from Cusabio

Category ELISA Kit
Sensitivity 5.86pg/ml
Range Request Information

Human Probable alpha-ketoglutarate-dependent dioxygenase ABH7 (ALKBH7) ELISA Kit - EKC35096 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 5.859 pg/ml
Range 1500 pg/ml-23.438 pg/ml

Human ALKBH7 ELISA Kit - E001402 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human ALKBH7 is typically less than 5.86 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

anti-ALKBH7 antibody - ARG57318 from Arigo Biolaboratories

Category ELISA Kit
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