IL18RAP

Gene Symbol IL18RAP
Entrez Gene 8807
Alt Symbol ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB
Species Human
Gene Type protein-coding
Description interleukin 18 receptor accessory protein
Other Description CD218 antigen-like family member B|IL-18 receptor accessory protein|IL-18 receptor beta|cluster of differentiation w218b|interleukin-1 receptor 7|interleukin-18 receptor accessory protein|interleukin-18 receptor beta
Swissprots B2RPJ3 Q53TT4 O95256 Q3KPE7 Q53TU5 Q3KPE8
Accessions AAY15049 AAY15080 CCF77059 EAX01791 O95256 AF077346 AAC72196 AK300026 BAG61837 BC069630 AAH69630 BC106764 AAI06765 BC106765 AAI06766 BC137474 AAI37475 BC137475 AAI37476 DN996214 DQ116957 AAZ52551 XM_011512087 XP_011510389 XM_011512088 XP_011510390 XM_011512089 XP_011510391 XR_923052 NM_003853 NP_003844
Function Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. {ECO:0000250, ECO:0000269|PubMed:9792649}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. {ECO:0000269|PubMed:10925275, ECO:0000269|PubMed:11046021, ECO:0000269|PubMed:9792649}.
Top Pathways Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD)

IL-18Rβ (N-14) - sc-107635 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-18Rβ (K-13) - sc-107634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-18Rβ (48986) - sc-80050 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-IL18R Beta antibody - ab203191 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Flow cytometry analysis of mouse cells labeling IL18R Beta (green, right histogram), using ab203191 at a 1/100 dilution, and negative control cells (blue, left histogram). Anti-rabbit secondary antibodies were used for the analysis.

Anti-IL18R Beta antibody - ab197832 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-IL18R Beta antibody (ab197832) at 1/450 dilution + RAW264.7 cell lysate at 40 µg

Anti-IL18R Beta antibody - ab93408 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-IL18R Beta antibody (ab93408) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-IL18R Beta antibody - ab57998 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57998 IL18R Beta antibody at 1ug/ml.

Anti-IL18R Beta antibody - ab47091 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL18R Beta antibody (ab47091) at 2 µg/mlLane 1 : human spleenLane 2 : mouse spleenLane 3 : mouse RAW cell lysate

Anti-IL18R Beta antibody [B-B46] - ab47258 from Abcam

Prices $359.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-B46

Anti-AcPL / IL18RAP Antibody (N-Terminus, APC) - LS-C244764 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (N-Terminus, AP) - LS-C244763 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (N-Terminus, Biotin) - LS-C244765 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (N-Terminus, FITC) - LS-C244766 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (N-Terminus, PE) - LS-C244767 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (aa117-240, Biotin) - LS-C299866 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (N-Terminus, Azide-free, HRP) - LS-C247650 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody - LS-C178494 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (aa396-548, Biotin) - LS-C300786 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (aa117-240, FITC) - LS-C304748 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (aa60-109) - LS-C40366 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IL18RAP antibody LS-C40366 Western blot of HepG2 cell lysate.

Anti-AcPL / IL18RAP Antibody - LS-C308454 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (aa20-129) - LS-C308456 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-AcPL / IL18RAP Antibody (aa396-548, FITC) - LS-C304966 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (N-Terminus) - LS-C327654 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AcPL / IL18RAP Antibody (aa396-548) - LS-C294873 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant AcPL / IL18RAP.
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