IL18RAP

Gene Symbol	IL18RAP
Entrez Gene	8807
Alt Symbol	ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB
Species	Human
Gene Type	protein-coding
Description	interleukin 18 receptor accessory protein
Other Description	CD218 antigen-like family member B|IL-18 receptor accessory protein|IL-18 receptor beta|cluster of differentiation w218b|interleukin-1 receptor 7|interleukin-18 receptor accessory protein|interleukin-18 receptor beta
Swissprots	B2RPJ3 Q53TT4 O95256 Q3KPE7 Q53TU5 Q3KPE8
Accessions	AAY15049 AAY15080 CCF77059 EAX01791 O95256 AF077346 AAC72196 AK300026 BAG61837 BC069630 AAH69630 BC106764 AAI06765 BC106765 AAI06766 BC137474 AAI37475 BC137475 AAI37476 DN996214 DQ116957 AAZ52551 XM_011512087 XP_011510389 XM_011512088 XP_011510390 XM_011512089 XP_011510391 XR_923052 NM_003853 NP_003844
Function	Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. {ECO:0000250, ECO:0000269|PubMed:9792649}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. {ECO:0000269|PubMed:10925275, ECO:0000269|PubMed:11046021, ECO:0000269|PubMed:9792649}.
Top Pathways	Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL18R Beta protein fragment - ab191972 from Abcam Category Protein Source HEK 293 cells Species Human

IL18R Beta protein (His-DHFR tag) - ab127389 from Abcam Category Protein Source E. coli Species Human

AcPL / IL18RAP Antibody Blocking Peptide - LS-E9787 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AcPL / IL18RAP Antibody Blocking Peptide - LS-E15511 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IL-18 R beta/IL-1 R7/ACPL Protein - H00008807-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human IL-18 R beta/IL-1 R7/ACPL Protein - H00008807-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

IL18RAP-Antibody-N-term-Blocking-Peptide - BP8797a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human IL-18 R beta/IL-1 R7 Fc Chimera, CF - 118-AP-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human IL18RAP protein - orb180310 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human IL18RAP protein - orb180309 from Biorbyt Category Protein Prices $204.00, $323.00, $850.00, $1,088.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

IL18RAP Blocking Peptide - 33R-6858 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CD218b / IL18RAP - H00008807-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD218b / IL18RAP - H00008807-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD218b / IL18RAP - H00008807-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

IL18RAP fusion protein - ag15927 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IL18RAP fusion protein - Ag17105 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human IL18RAP, His tagged - IL18RAP-3150H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human IL18RAP, Fc Chimera - IL18RAP-1073H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-tagged - IL18RAP-1658H from Creative Biomart Category Protein Source NSO Cells.

Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-His - IL18RAP-2255H from Creative Biomart Category Protein Source Human Cells .

Recombinant Interleukin 18 Receptor Accessory Protein (IL18RAP) - RPB655Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Interleukin 18 Receptor Accessory Protein (IL18RAP) - RPB655Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Interleukin 18 Receptor Accessory Protein (IL18RAP) - RPB655Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Human IL18RAP / IL1R7 Protein (Fc Tag) - 10176-H02H-100 from Sino Biological Category Protein Prices $198.00, $298.00 Sizes 100 µg, 200 µg Source Human Cells Species Human

Human IL18RAP / IL1R7 Protein (His Tag) - 10176-H08H-100 from Sino Biological Category Protein Prices $138.00, $348.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

Search more