Gene Symbol | GMNN |
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Entrez Gene | 51053 |
Alt Symbol | Gem |
Species | Human |
Gene Type | protein-coding |
Description | geminin, DNA replication inhibitor |
Other Description | geminin |
Swissprots | O75496 Q9H1Z1 B3KMM8 |
Accessions | CBL95030 CDH63540 EAW55465 EAW55466 O75496 AF067855 AAC39787 AK021685 BAG51040 AK222992 BAD96712 AK315743 AL558330 BC005185 AAH05185 BC005389 AAH05389 BF977182 BG777134 BM699599 CB131959 CB992796 HQ448314 ADQ32794 XM_005249159 XP_005249216 XM_011514651 XP_011512953 NM_001251989 NP_001238918 NM_001251990 NP_001238919 NM_001251991 NP_001238920 NM_015895 NP_056979 |
Function | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. |
Subcellular Location | Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus. |
Human GEM protein fragment - ab158511 from Abcam
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Human Geminin full length protein - ab40570 from Abcam
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Human Geminin full length protein - ab86447 from Abcam
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Human Geminin peptide - ab12408 from Abcam
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GEM / KIR Antibody Blocking Peptide - LS-E15535 from LifeSpan Bioscience
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GEM / KIR Antibody Blocking Peptide - LS-E15534 from LifeSpan Bioscience
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GEM / KIR Antibody Blocking Peptide - LS-E27877 from LifeSpan Bioscience
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Geminin Antibody Blocking Peptide - LS-E7780 from LifeSpan Bioscience
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Geminin Recombinant Protein - H00051053-P01 from Novus Biologicals
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Geminin Partial Recombinant Protein - H00051053-Q01 from Novus Biologicals
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Recombinant Human GEM Protein - H00002669-Q01 from Novus Biologicals
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Geminin Protein - NBC1-18423 from Novus Biologicals
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GMNN-Antibody-Center-Y111-Blocking-peptide - BP5227c from Abgent, a WuXi AppTec company
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Geminin Protein - GTX116125-pro from GeneTex
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GMNN Recombinant Protein - GTX48260-PRO from GeneTex
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GMNN Protein (OPPA01453) - OPPA01453 from Aviva Systems Biology
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GEM Blocking Peptide - 33R-4348 from Fitzgerald
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GEM Blocking Peptide - 33R-3073 from Fitzgerald
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Gem Blocking Peptide - 33R-7463 from Fitzgerald
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Geminin protein (His tag) - 80R-1016 from Fitzgerald
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GEM Peptide - AC21-2667-P from Abcore
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Geminin (His-tag) - AR09030PU-L from Acris Antibodies
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Geminin (His-tag) - AR09030PU-N from Acris Antibodies
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Geminin - H00051053-P01-10 from Acris Antibodies
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Geminin - H00051053-P01-25 from Acris Antibodies
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