GMNN

Gene Symbol GMNN
Entrez Gene 51053
Alt Symbol Gem
Species Human
Gene Type protein-coding
Description geminin, DNA replication inhibitor
Other Description geminin
Swissprots O75496 Q9H1Z1 B3KMM8
Accessions CBL95030 CDH63540 EAW55465 EAW55466 O75496 AF067855 AAC39787 AK021685 BAG51040 AK222992 BAD96712 AK315743 AL558330 BC005185 AAH05185 BC005389 AAH05389 BF977182 BG777134 BM699599 CB131959 CB992796 HQ448314 ADQ32794 XM_005249159 XP_005249216 XM_011514651 XP_011512953 NM_001251989 NP_001238918 NM_001251990 NP_001238919 NM_001251991 NP_001238920 NM_015895 NP_056979
Function Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
Subcellular Location Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus.

Geminin Antibody - 5165 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using Geminin Antibody.

Geminin (H-3) - sc-374187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Geminin (H-3): sc-374187. Western blot analysis of Geminin expression in non-transfected: sc-117752 (A) and mouse Geminin transfected: sc-120468 (B) 293T whole cell lysates.

Geminin (A-3) - sc-74496 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Geminin (A-3): sc-74496. Western blot analysis of human recombinant Geminin.

Geminin (FL-209) - sc-13015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Geminin (FL-209): sc-13015. Western blot analysis of Geminin expression in non-transfected 293T: sc-117752 (A), mouse Geminin transfected 293T: sc-120468 (B) and MM-142 (C) whole cell lysates.

Geminin (F-7) - sc-74456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Geminin (F-7): sc-74456. Western blot analysis of human recombinant Geminin under reducing conditions.

Geminin (M-16) - sc-8450 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
eminin (M-16): sc-8450. Western blot analysis of human recombinant Geminin under reducing conditions.

Geminin (C-16) - sc-8448 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Geminin (C-16): sc-8448. Western blot analysis of human recombinant geminin (GMNN).

Geminin (N-18) - sc-8449 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Geminin (N-18): sc-8449. Western blot analysis of human recombinant geminin (GMNN).

Anti-Geminin antibody - ab12147 from Abcam

Prices $400.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Geminin antibody (ab12147) at 1/500 dilutionLane 1 : 293 lysateLane 2 : 293 lysate with Human Geminin peptide (ab12408) at 1 µg/mlLysates/proteins at 5 µg/ml per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-Geminin antibody - ab104306 from Abcam

Prices $388.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Geminin antibody (ab104306) at 5 µg/ml + Immunogen at 0.2 µg

Anti-Geminin antibody - ab175799 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of U2OS cells labelling Geminin with ab175799 at 1:1000. Cells were fixed with PFA and permeabilized with methanol for 2 minutes. Cells were incubated with the primary anitbody overnight at room temperature. From left to right - Geminin, CyclinB, DAPI, Merge.

Anti-Geminin antibody - ab187553 from Abcam

Prices $382.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human liver cancer tissue labelling Geminin with ab187553 at 1/200. Magnification: 200x.

Anti-Geminin antibody - ab84423 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84423 staining Geminin in Human tonsil tissue sections by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with formaldehyde; antigen retrieval was by heat mediation in EDTA pH8.0 for 20 minutes at 100°C. Samples were incubated with primary antibody (1/40) for 20 minutes at 25°C. A HPR-conjugated Mouse anti-rabbit IgG polyclonal was used as the secondary antibody.See Abreview

Anti-Geminin antibody [EPR14637] - ab195047 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14637
All lanes : Anti-Geminin antibody [EPR14637] (ab195047) at 1/500 dilutionLane 1 : Untreated HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell lysateLane 2 : HeLa (Human epithelial cells from cervix adenocarcinoma) treated with thymidine whole cell lysateLane 3 : HeLa (Human epithelial cells from cervix adenocarcinoma) treated with nocodazole whole cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilutiondeveloped using the ECL technique

Anti-Geminin Antibody (aa50-100) - LS-C286437 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Geminin by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Geminin used at a dilution of 1:250.

Anti-Geminin Antibody (aa96-123) - LS-C166536 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GMNN Antibody (Center Y111) IHC of formalin-fixed and paraffin-embedded lung tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry.

Anti-Geminin Antibody (aa50-100) - LS-C203087 from LifeSpan Bioscience

Prices $245.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal
Western blot of human recombinant Geminin fusion protein using Geminin Antibody, pAb, Rabbit (1 ug/ml). The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG. Predicted Size: 38 kD. Observed Size: 38 kD.

Anti-Geminin Antibody (aa50-100) - LS-C286034 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Geminin by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Geminin used at a dilution of 1:5000 (0.2 Detection: DAB.

Anti-Geminin Antibody - LS-C333979 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human breast cancer using GMNN antibody at dilution of 1:200 (200x lens).

Anti-Geminin Antibody (clone 1A8) IHC-plus™ - LS-B6226 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1A8
Anti-GMNN / Geminin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6226 concentration 1 ug/ml.

Anti-Geminin Antibody - LS-C23807 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal

Anti-Geminin Antibody (aa50-100) - LS-C66459 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Geminin Antibody (C-Terminus) - LS-C66460 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Geminin Antibody (aa50-100) - LS-C92562 from LifeSpan Bioscience

Prices $295.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal

Anti-Geminin Antibody (N-Terminus) - LS-C92563 from LifeSpan Bioscience

Prices $295.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal
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