OSBP

Gene Symbol	OSBP
Entrez Gene	5007
Alt Symbol	OSBP1
Species	Human
Gene Type	protein-coding
Description	oxysterol binding protein
Other Description	oxysterol-binding protein 1
Swissprots	P22059 Q6P524
Accessions	AAG28373 EAW73849 P22059 AF185696 AAG17011 AK299071 BAG61137 AK310538 BC011581 AAH11581 BC017975 BC051350 BC063121 AAH63121 M86917 AAA59973 NM_002556 NP_002547
Function	Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25- hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. {ECO:0000269|PubMed:15746430, ECO:0000269|PubMed:18450749}.
Subcellular Location	Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note=When bound to oxysterols, translocates to the periphery of Golgi membranes.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11278871}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

oxysterol binding protein, ELISA Kit - MBS9334597 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human OSBP ELISA Kit - E028006 from Biobool Category ELISA Kit

anti-OSBP1 antibody - ARG63390 from Arigo Biolaboratories Category ELISA Kit

anti-OSBP antibody - ARG63750 from Arigo Biolaboratories Category ELISA Kit

Oxysterol-binding protein 1, ELISA Kit - MBS284584 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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