OSBP

Gene Symbol OSBP
Entrez Gene 5007
Alt Symbol OSBP1
Species Human
Gene Type protein-coding
Description oxysterol binding protein
Other Description oxysterol-binding protein 1
Swissprots P22059 Q6P524
Accessions AAG28373 EAW73849 P22059 AF185696 AAG17011 AK299071 BAG61137 AK310538 BC011581 AAH11581 BC017975 BC051350 BC063121 AAH63121 M86917 AAA59973 NM_002556 NP_002547
Function Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25- hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability. {ECO:0000269|PubMed:15746430, ECO:0000269|PubMed:18450749}.
Subcellular Location Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note=When bound to oxysterols, translocates to the periphery of Golgi membranes.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:11278871}.

Human OSBP1 peptide - ab23121 from Abcam

Category Peptide
Species Human

Human OSBP1 protein fragment - ab152583 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab152583 stained with Coomassie Blue.

OSBP1 peptide (395-410) - ab45716 from Abcam

Category Peptide
Species Human

OSBP Antibody Blocking Peptide - LS-E25627 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OSBP Antibody Blocking Peptide - LS-E22042 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OSBP Antibody Blocking Peptide - LS-E25856 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human OSBP1 Protein - H00005007-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

OSBP-Antibody-Center-Blocking-peptide - BP11453c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

OSBP blocking peptide - GTX89571-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat, Bovine

OSBP1 (C Terminus) blocking peptide - GTX25915-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

OSBP Immunizing peptide - orb17942 from Biorbyt

Category Peptide
Prices $247.00
Sizes 100 μg
Species Human, Mouse, Rat

OSBP1 Peptide - AC21-0458-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

OSBP1 Peptide - AC21-0686-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

OSBP - H00005007-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

OSBP - H00005007-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

OSBP Peptide - 46-113P from ProSci

Category Peptide
Species Human

OSBP1 Peptide - 46-114P from ProSci

Category Peptide
Species Human

OSBP fusion protein - ag1578 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Oxysterol-binding protein 1(OSBP) ,partial - CSB-YP017243HU CSB-EP017243HU CSB-BP017243HU CSB-MP017243HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

OSBP - TP304250 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
OSBP

OSBP, Peptide - MBS426165 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Bovine

OSBP1, Peptide - MBS428057 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

Recombinant Oxysterol Binding Protein (OSBP) - RPC694Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

OSBP1 Recombinant Protein Antigen - NBP2-47343PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

OSBP1 Recombinant Protein Antigen - NBP2-47342PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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