UXT

Gene Symbol UXT
Entrez Gene 8409
Alt Symbol ART-27, STAP1
Species Human
Gene Type protein-coding
Description ubiquitously-expressed, prefoldin-like chaperone
Other Description SKP2-associated alpha PFD 1|androgen receptor trapped clone 27 protein|protein UXT|ubiquitously expressed transcript protein
Swissprots Q9Y6E5 Q5JZG3 Q9UBK9 B2R561
Accessions CAH05296 CAH05297 EAW59324 EAW59325 EAW59326 Q9UBK9 AF083241 AAD39839 AF083242 AAD39840 AF092737 AAD28698 AK223320 AK312072 BAG35008 BC000720 AAH00720 BC008890 AAH08890 BM471483 BQ681820 DA372561 EL949569 NM_004182 NP_004173 NM_153477 NP_705582 NR_045559 NR_045560
Function Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription (AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation (PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function (PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584).
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus.
Tissue Specificity Ubiquitous. Expressed in prostate epithelial cells. Overexpressed in a number of tumor tissues (PubMed:16221885). Highest levels in the heart, skeletal muscle, pancreas, kidney, liver, adrenal gland, peripheral blood leukocytes, lymph node, prostate, and thyroid and the lowest levels in bladder and uterus. {ECO:0000269|PubMed:11854421, ECO:0000269|PubMed:16221885, ECO:0000269|PubMed:17635584, ECO:0000269|PubMed:21730289}.

UXT (J-19) - sc-102152 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
UXT (J-19): sc-102152. Western blot analysis of UXT expression in Hep G2 whole cell lysate.

Anti-UXT antibody - ab168678 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-UXT antibody (ab168678) at 1 µg/ml + Jurkat cell lysate at 50 µgdeveloped using the ECL technique

Anti-UXT Antibody (C-Terminus) - LS-C345457 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of UXT Antibody with human U937 Whole Cell lysate.

Anti-UXT Antibody (N-Terminus) - LS-C81619 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 15%.

Anti-UXT Antibody (N-Terminus) - LS-C81133 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%.

Anti-UXT Antibody - LS-C333147 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse brain, using UXT antibody.

Anti-UXT Antibody (aa37-49) IHC-plus™ - LS-B10293 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-UXT antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10293 concentration 5 ug/ml.

UXT Antibody - NBP2-31717 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: UXT Antibody [NBP2-31717] - Staining of human lymph node shows strong membranous and cytoplasmic positivity in germinal center cells and non-germinal center cells.

UXT Antibody - NBP1-54826 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UXT Antibody [NBP1-54826] - HepG2 cell lysate, concentration 1.25ug/ml.

UXT Antibody - H00008409-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: UXT Antibody [H00008409-B01P] - Analysis of UXT expression in Jurkat.

UXT Antibody - H00008409-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: UXT Antibody [H00008409-B01] - analysis of UXT expression in transfected 293T cell line by UXT MaxPab polyclonal antibody (B01). Lane 1: UXT transfected lysate (19.60 KDa). Lane 2: Non-transfected lysate.

UXT Antibody - NBP1-00129 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: UXT Antibody [NBP1-00129] - (0.03ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Ubiquitously expressed transcript Antibody - bs-6749R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit

Anti-UXT antibody produced in rabbit - HPA058400 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UXT: <B>Cat. No. HPA058400</B>: Immunohistochemical staining of Human lymph node shows strong membranous and cytoplasmic positivity in germinal center cells and non-germinal center cells.

Anti-UXT (AB2) antibody produced in rabbit - AV51213 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV51213</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 2.5 μg/mL in cell type HepG2

Anti-UXT antibody produced in goat - SAB2501091 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UXT: <B>Cat. No. SAB2501091</B>: (0.03 μg/mL) staining of Human Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-UXT (AB1) antibody produced in rabbit - AV47942 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV47942</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2

UXT Antibody - C-terminal region (ARP47941_P050) - ARP47941_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UXT antibody - N-terminal region (ARP47942_T100) - ARP47942_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UXT antibody - N-terminal region (ARP51213_T100) - ARP51213_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UXT-Antibody - AF2139a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2139a (0.03 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

UXT Antibody (OABF01744) - OABF01744 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UXT Antibody (OAEB02017) - OAEB02017 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

UXT antibody - 70R-21227 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

UXT Polyclonal Antibody - A4217 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cells, using UXT antibody.
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