POMK

Gene Symbol	POMK
Entrez Gene	84197
Alt Symbol	MDDGA12, MDDGC12, SGK196
Species	Human
Gene Type	protein-coding
Description	protein-O-mannose kinase
Other Description	Sugen kinase 196|probable inactive protein kinase-like protein SgK196|protein O-mannose kinase|protein kinase-like protein SgK196
Swissprots	Q9H5K3
Accessions	EAW63187 Q9H5K3 BC101548 AAI01549 BC113703 AAI13704 BQ365114 DA074115 DA330953 DA383787 DA818523 EH337134 XM_011544668 XP_011542970 XM_011544669 XP_011542971 NM_001277971 NP_001264900 NM_032237 NP_115613
Function	Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif. {ECO:0000269|PubMed:23519211, ECO:0000269|PubMed:23929950}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity	Highest expression is observed in brain, skeletal muscle, kidney and heart in fetal and adult tissues. {ECO:0000269|PubMed:24925318}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SGK196 full length protein - ab164520 from Abcam Category Protein Source Wheat germ Species Human

Human SGK196 full length protein - ab201392 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human SGK196 protein fragment - ab164521 from Abcam Category Protein Source Wheat germ Species Human

POMK / SGK196 Antibody Blocking Peptide - LS-E3154 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POMK / SGK196 Antibody Blocking Peptide - LS-E18080 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FLJ23356 Protein - H00084197-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FLJ23356 Protein - H00084197-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FLJ23356-Antibody-C-term-Blocking-peptide - BP11865b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SGK196 - H00084197-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SGK196 - H00084197-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SGK196 - H00084197-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SGK196 - H00084197-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human Protein kinase-like protein SgK196(SGK196) - CSB-YP863985HU CSB-EP863985HU CSB-BP863985HU CSB-MP863985HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SGK196 - TP322797 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FLJ23356 Recombinant Protein Antigen - NBP2-13302PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SGK196 Peptide, Human - M34GP14135H from Creative Peptides Category Peptide Source Synthetic. Species Human

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