POMK

Gene Symbol POMK
Entrez Gene 84197
Alt Symbol MDDGA12, MDDGC12, SGK196
Species Human
Gene Type protein-coding
Description protein-O-mannose kinase
Other Description Sugen kinase 196|probable inactive protein kinase-like protein SgK196|protein O-mannose kinase|protein kinase-like protein SgK196
Swissprots Q9H5K3
Accessions EAW63187 Q9H5K3 BC101548 AAI01549 BC113703 AAI13704 BQ365114 DA074115 DA330953 DA383787 DA818523 EH337134 XM_011544668 XP_011542970 XM_011544669 XP_011542971 NM_001277971 NP_001264900 NM_032237 NP_115613
Function Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif. {ECO:0000269|PubMed:23519211, ECO:0000269|PubMed:23929950}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Highest expression is observed in brain, skeletal muscle, kidney and heart in fetal and adult tissues. {ECO:0000269|PubMed:24925318}.

FLJ23356 CRISPR/Cas9 KO Plasmid (h) - sc-406964 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 HDR Plasmid (h) - sc-406964-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 Double Nickase Plasmid (h) - sc-406964-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 Double Nickase Plasmid (h2) - sc-406964-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 CRISPR Activation Plasmid (h) - sc-406964-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 CRISPR Activation Plasmid (h2) - sc-406964-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 Lentiviral Activation Particles (h) - sc-406964-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 Lentiviral Activation Particles (h2) - sc-406964-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 siRNA (h) - sc-77530 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FLJ23356 shRNA Plasmid (h) - sc-77530-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FLJ23356 shRNA (h) Lentiviral Particles - sc-77530-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FLJ23356 RNAi - H00084197-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® siRNA - SIHK2060 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2058 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2059 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN19226 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19226 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01719 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01719

POMK siRNA (Human) - CRJ3349 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FLJ23356 RNAi - H00084197-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FLJ23356 CRISPR/Cas9 KO Plasmid (h2) - sc-406964-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FLJ23356 HDR Plasmid (h2) - sc-406964-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human Sgk196 (NM_032237.3) - SHH406260 from Creative biogene

Category siRNA
Species Reactivities Human

Human POMK siRNA - orb273850 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POMK shRNA Plasmid (Human) - CHJ3349 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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