Gene Symbol | RNF212 |
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Entrez Gene | 285498 |
Alt Symbol | ZHP3 |
Species | Human |
Gene Type | protein-coding |
Description | ring finger protein 212 |
Other Description | probable E3 SUMO-protein ligase RNF212 |
Swissprots | C9J8N0 Q8N8U7 Q495C1 Q8IY99 Q86W82 Q495C0 |
Accessions | EAW82610 EAW82611 EAW82612 EAW82613 EAW82614 Q495C1 AK096160 BAC04714 AK124578 AK310043 BC036250 AAH36250 BC050356 AAH50356 BC101258 AAI01259 BC101259 AAI01260 BC101260 AAI01261 BC101261 AAI01262 BG701603 BI460105 DB159979 XM_005272274 XP_005272331 XM_011513438 XP_011511740 XM_011513439 XP_011511741 XM_011513440 XP_011511742 XM_011513441 XP_011511743 XM_011513442 XP_011511744 XM_011513443 XP_011511745 XM_011513444 XP_011511746 XM_011513445 XP_011511747 XM_011513446 XP_011511748 XR_246609 XR_924933 XR_924936 XR_924937 NM_001131034 NP_001124506 NM_001193318 NP_001180247 NM_194439 NP_919420 |
Function | SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Associates to the synaptonemal complex. Localizes to a minority of double-strand breaks (DSBs) sites. Marks crossover sites during midpachynema (By similarity). {ECO:0000250}. |
RNF212 (I-14) - sc-163304 from Santa Cruz Biotechnology
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Anti-LOC285498 antibody - ab154021 from Abcam
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Anti-LOC285498 antibody - ab83874 from Abcam
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Anti-LOC285498 antibody - ab58024 from Abcam
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Anti-LOC285498 antibody [EPR8796] - ab151540 from Abcam
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Anti-RNF212 Antibody (aa70-82) - LS-C87289 from LifeSpan Bioscience
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Anti-RNF212 Antibody (aa72-121) - LS-C102034 from LifeSpan Bioscience
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RNF212 Antibody - NBP2-20182 from Novus Biologicals
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RNF212 Antibody - NBP1-55083 from Novus Biologicals
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RNF212 Antibody - NBP1-83471 from Novus Biologicals
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RNF212 Antibody - H00285498-B01P from Novus Biologicals
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RNF212 Antibody - NBP1-20969 from Novus Biologicals
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RNF212 Antibody (5H3) - H00285498-M01 from Novus Biologicals
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Anti-RNF212 antibody produced in rabbit - HPA037651 from Sigma-Aldrich
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Anti-RNF212 antibody produced in rabbit - SAB2102029 from Sigma-Aldrich
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Monoclonal Anti-LOC285498 antibody produced in mouse - WH0285498M1 from Sigma-Aldrich
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RNF212 antibody - middle region (ARP43487_P050) - ARP43487_P050 from Aviva Systems Biology
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RNF212-Antibody-internal-region - AF2771a from Abgent, a WuXi AppTec company
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RNF212 Antibody (OAEB00243) - OAEB00243 from Aviva Systems Biology
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RNF212 antibody - 70R-19927 from Fitzgerald
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RNF212 antibody - 70R-2823 from Fitzgerald
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RNF212 Polyclonal Antibody - A3569 from ABclonal
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Ring Finger Protein 212 Antibody - abx115297 from Abbexa
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RNF212 Antibody - abx002581 from Abbexa
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RNF212 antibody - 21178-1-AP from Acris Antibodies
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