TP53RK

Gene Symbol	TP53RK
Entrez Gene	112858
Alt Symbol	BUD32, C20orf64, Nori-2, Nori-2p, PRPK, dJ101A2
Species	Human
Gene Type	protein-coding
Description	TP53 regulating kinase
Other Description	EKC/KEOPS complex subunit TP53RK|TP53-regulating kinase|atypical serine/threonine protein kinase TP53RK|p53-related protein kinase
Swissprots	Q6NZ60 Q3T977 B3KU44 Q9NQE6 Q96FM7 Q5JZ01 Q96S44
Accessions	EAW75727 Q96S44 AB017505 BAB61875 AB065434 BAB62041 AK096502 BAG53306 AK315182 BAG37623 BC009727 AAH09727 BC010637 AAH10637 BC019621 BC035461 BC066309 AAH66309 BM702732 NM_033550 NP_291028
Function	Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation. {ECO:0000250, ECO:0000269|PubMed:11546806}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:22912744}.
Tissue Specificity	Highly expressed in testis. Weakly expressed in heart kidney and spleen.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TP53RK-cDNA-Clone - DC02748 from Abgent, a WuXi AppTec company Prices $342.90 Sizes 10 µg Species Human Accession BC009727

TP53RK - MBS1268104 from MyBioSource Species Human Accession BC009727

Human TP53RK cDNA clone(NM_033550.3) - CDFG006917 from Creative Biomart Species Human Accession NM_033550.3

Human TP53RK cDNA clone(NM_033550.3) - CDFG006918 from Creative Biomart Species Human Accession NM_033550.3

Human TP53RK ORF Clone(NM_033550.3) - CDCR314092 from Creative Biomart Species Human Accession NM_033550.3

Human TP53RK ORF Clone(NM_033550.3) - CDCR314093 from Creative Biomart Species Human Accession NM_033550.3

human TP53RK ORF clone - CDCH094132 from Creative Biomart Species Human Accession NM_033550

human TP53RK ORF clone - CDCH094133 from Creative Biomart Species Human Accession NM_033550

Human TP53RK ORF Clone(NM_033550.3) - CDCL179393 from Creative Biomart Species Human Accession NM_033550.3

Human TP53RK Gene cDNA clone plasmid - HG12270-G from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12270-ACG from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid - HG12270-UT from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12270-ACR from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG12270-ANR from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, C-His tag - HG12270-CH from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12270-NF from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12270-NM from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12270-CF from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, C-HA tag - HG12270-CY from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12270-CM from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG12270-ANG from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, N-HA tag - HG12270-NY from Sino Biological Species Human

Human TP53RK Gene ORF cDNA clone expression plasmid, N-His tag - HG12270-NH from Sino Biological Species Human

Human TP53RK ORF Clone(NM_033550.3) - CDCR314092 from Creative biogene Species Human

Human TP53RK ORF Clone (BC009727) - CDCS416529 from Creative biogene Species Human Accession Q96S44

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