IGF2R

Gene Symbol	IGF2R
Entrez Gene	3482
Alt Symbol	CD222, CIMPR, M6P-R, MPR1, MPRI
Species	Human
Gene Type	protein-coding
Description	insulin-like growth factor 2 receptor
Other Description	300 kDa mannose 6-phosphate receptor|CI Man-6-P receptor|CI-MPR|IGF-II receptor|M6P/IGF2 receptor|M6P/IGF2R|M6PR|MPR 300|cation-independent mannose-6 phosphate receptor|cation-independent mannose-6-phosphate receptor|insulin-like growth factor II receptor
Swissprots	P11717 Q96PT5 Q7Z7G9
Accessions	AAF16870 AAK56918 AAL04402 AAP37954 CAA58672 CAA58673 CAA58674 CAA58675 CAA62977 EAW47607 P11717 AB209668 BAD92905 AK300848 BAG62499 BC172256 AAI72256 J03528 AAA59866 S80783 AAB35664 S80785 AAB35665 S80797 AAD14337 Y00285 CAA68395 XR_942419 NM_000876 NP_000867
Function	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. {ECO:0000269|PubMed:10900005}.
Subcellular Location	Lysosome membrane {ECO:0000269|PubMed:10900005}; Single-pass type I membrane protein {ECO:0000269|PubMed:10900005}. Note=Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human IGF2R / CD222 ELISA Kit (Sandwich ELISA) - LS-F4877 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.221 ng/ml Range 0.625-40 ng/ml

Human IGF2R / CD222 ELISA Kit (Sandwich ELISA) - LS-F10497 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 0.625-40 ng/ml

Human IGF2R / Cation-independent mannose-6-phosphate Receptor ELISA Kit - RAB0680 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human IGF-II R DuoSet ELISA - DY2447 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 156.00 - 10,000 pg/mL

Human IGF2R ELISA kit - 55R-2193 from Fitzgerald Category ELISA Kit Prices $545.00 Sizes 96 tests

Human IGF2R ELISA kit - orb215858 from Biorbyt Category ELISA Kit Prices $612.00 Sizes 96 well Sensitivity <10 pg/ml

Human IGF2R ELISA Kit - abx151910 from Abbexa Category ELISA Kit Sensitivity 0.244 ng/ml Range 0.625 ng/ml - 40 ng/ml

Cation-independent mannose-6-phosphate receptor, IGF2R, Human, ELISA Kit - E1629h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Insulin Like Growth Factor 2 Receptor, IGF2R, Human, ELISA Kit - E-EL-H0440 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.375 Range 0.625-40ng/mL

Insulin Like Growth Factor 2 Receptor (IGF2R), Human, ELISA Kit - SEB629Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.244ng/mL Range 0.625-40ng/mL

Insulin-like growth factors 2 receptor, IGF-2R, Human, ELISA Kit - CSB-E11267h from ARP American Research Products Category ELISA Kit Prices $366.00, $496.00, $497.00, $499.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 80 pg/ml Range 312.5 pg/ml -20000 pg/ml

Ion-independent mannose-6-phosphate receptor (IGF2R), Human, ELISA Kit - E01I0131 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Insulin Like Growth Factor 2 Receptor, IGF2R, Rabbit, ELISA Kit - E-EL-RB1518 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Insulin Like Growth Factor 2 Receptor, IGF2R, Chicken, ELISA Kit - E-EL-Ch0350 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Insulin Like Growth Factor 2 Receptor, IGF2R, Porcine, ELISA Kit - E-EL-P1086 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Insulin Like Growth Factor 2 Receptor, IGF2R, Sheep, ELISA Kit - E-EL-S0467 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Insulin Like Growth Factor 2 Receptor, IGF2R, Monkey, ELISA Kit - E-EL-MK2184 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human IGF2R(Insulin Like Growth Factor 2 Receptor) ELISA Kit - E-EL-H0440 from Elabscience Category ELISA Kit Sensitivity 0.38 ng/mL Range 0.63—40 ng/mL

Human IGF2R (Insulin Like Growth Factor 2 Receptor) CLIA Kit - E-CL-H0359 from Elabscience Category CLIA Kit Sensitivity 75.00 pg/mL Range Average Recovery (%)

Cation-independent mannose-6-phosphate receptor, ELISA Kit - MBS177544 from MyBioSource Category ELISA Kit Prices $455.00 Sizes 1x96 wells Sensitivity <10pg/ml Range 156pg/ml-10,000pg/ml

cation-independent mannose-6-phosphate receptor (IGF2R), ELISA Kit - MBS7232839 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

IGF2R, ELISA Kit - MBS2500187 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

IGF2R, ELISA Kit - MBS2504539 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.375ng/mL Range 0.625-40ng/mL

IGF2R, ELISA Kit - MBS2512523 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.375ng/mL Range 0.625-40ng/mL

IGF2R, ELISA Kit - MBS2513344 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

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