Gene Symbol | TREML2 |
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Entrez Gene | 79865 |
Alt Symbol | C6orf76, TLT-2, TLT2, dJ238O23.1 |
Species | Human |
Gene Type | protein-coding |
Description | triggering receptor expressed on myeloid cells-like 2 |
Other Description | trem-like transcript 2 protein|triggering receptor expressed on myeloid cells-like protein 2 |
Swissprots | Q08AP9 Q9H8E9 Q08AP8 Q5T2D2 Q8IWY0 |
Accessions | EAX04035 EAX04036 Q5T2D2 AF534824 AAO15022 AJ420509 AK023755 BAB14668 AY358171 AAQ88538 BC125078 AAI25079 BC125079 AAI25080 XM_011514917 XP_011513219 NM_024807 NP_079083 |
Function | Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}. |
Human TREML2 protein fragment - ab191918 from Abcam
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TLT2 / TREML2 Antibody Blocking Peptide - LS-E18014 from LifeSpan Bioscience
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TLT2 / TREML2 Antibody Blocking Peptide - LS-E18015 from LifeSpan Bioscience
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Recombinant Human TREML2/TLT-2 Fc Chimera, CF - 3259-TL-050 from R&D Systems
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Human TREML2 protein - orb180431 from Biorbyt
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Human TREML2 His tag protein - orb83897 from Biorbyt
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TREML2 Blocking Peptide - 33R-3547 from Fitzgerald
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TREML2 Blocking Peptide - 33R-9100 from Fitzgerald
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TREML2 fusion protein - ag18468 from Proteintech Group
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Recombinant Human TREML2, His tagged - TREML2-3227H from Creative Biomart
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Recombinant Human TREML2, Fc Chimera - TREML2-521H from Creative Biomart
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Human TREML2 / TLT2 Protein (His Tag) - 11655-H08H-50 from Sino Biological
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Recombinant Human Trem-like transcript 2 protein(TREML2) - CSB-YP729201HU CSB-EP729201HU CSB-BP729201HU CSB-MP729201HU from Cusabio
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TREML2 - TP721080 from Acris Antibodies
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Recombinant Human TREML2 / TLT2 Protein (His tag) - PKSH031041 from Elabscience
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TREML2 Peptide, Human - M34GP16551H from Creative Peptides
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Human TREML2 / TLT2 Protein (His Tag) - 11655-H08H from ABclonal
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Recombinant Human TREML2/TLT-2 Fc Chimera Protein, CF - 3259-TL from Novus Biologicals
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Human TREML2 protein - orb392633 from Biorbyt
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