Gene Symbol | TREML2 |
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Entrez Gene | 79865 |
Alt Symbol | C6orf76, TLT-2, TLT2, dJ238O23.1 |
Species | Human |
Gene Type | protein-coding |
Description | triggering receptor expressed on myeloid cells-like 2 |
Other Description | trem-like transcript 2 protein|triggering receptor expressed on myeloid cells-like protein 2 |
Swissprots | Q08AP9 Q9H8E9 Q08AP8 Q5T2D2 Q8IWY0 |
Accessions | EAX04035 EAX04036 Q5T2D2 AF534824 AAO15022 AJ420509 AK023755 BAB14668 AY358171 AAQ88538 BC125078 AAI25079 BC125079 AAI25080 XM_011514917 XP_011513219 NM_024807 NP_079083 |
Function | Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}. |
TREML2 (A-14) - sc-109096 from Santa Cruz Biotechnology
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TREML2 (C-14) - sc-109097 from Santa Cruz Biotechnology
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Anti-TREML2 antibody - ab74837 from Abcam
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Anti-TLT2 / TREML2 Antibody (Extracellular Domain) - LS-C39846 from LifeSpan Bioscience
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Anti-TLT2 / TREML2 Antibody (aa25-270, clone 12K189) - LS-C182965 from LifeSpan Bioscience
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Anti-TLT2 / TREML2 Antibody (aa25-270, clone 12K189, APC) - LS-C182964 from LifeSpan Bioscience
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Anti-TLT2 / TREML2 Antibody (aa25-270, clone 12K189, PE) - LS-C182966 from LifeSpan Bioscience
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Anti-TLT2 / TREML2 Antibody (aa25-270) - LS-C184916 from LifeSpan Bioscience
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Anti-TLT2 / TREML2 Antibody (aa101-150) - LS-C117153 from LifeSpan Bioscience
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Anti-TLT2 / TREML2 Antibody (aa188-237) IHC-plus⢠- LS-B8196 from LifeSpan Bioscience
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TREML2/TLT-2 Antibody [Unconjugated] - AF3259 from Novus Biologicals
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TREML2/TLT-2 Antibody - NBP1-70737 from Novus Biologicals
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TREML2 Polyclonal Antibody - bs-2737R from Bioss
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Anti-TREML2 antibody produced in rabbit - AV49878 from Sigma-Aldrich
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Anti-TREML2 antibody produced in rabbit - HPA054368 from Sigma-Aldrich
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Anti-TREML2 antibody produced in rabbit - SAB2106870 from Sigma-Aldrich
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TREML2 antibody - N-terminal region (ARP49877_P050) - ARP49877_P050 from Aviva Systems Biology
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TREML2 antibody - middle region (ARP49878_P050) - ARP49878_P050 from Aviva Systems Biology
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Human TREML2/TLT-2 Antibody - AF3259 from R&D Systems
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Human TREML2/TLT-2 Affinity Purified Polyclonal Ab, Goat IgG - AF3259-SP from R&D Systems
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Mouse TREML2/TLT-2 Antibody - MAB6707 from R&D Systems
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Mouse TREML2/TLT-2 MAb (Clone 656906), Rat IgG2A - MAB6707-SP from R&D Systems
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Mouse TREML2/TLT-2 Antibody - AF6354 from R&D Systems
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Mouse TREML2/TLT-2 Affinity Purified Polyclonal Ab, Sheep IgG - AF6354-SP from R&D Systems
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Mouse TREML2/TLT-2 APC-conjugated Antibody - FAB6707A from R&D Systems
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