Gene Symbol | TREML2 |
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Entrez Gene | 79865 |
Alt Symbol | C6orf76, TLT-2, TLT2, dJ238O23.1 |
Species | Human |
Gene Type | protein-coding |
Description | triggering receptor expressed on myeloid cells-like 2 |
Other Description | trem-like transcript 2 protein|triggering receptor expressed on myeloid cells-like protein 2 |
Swissprots | Q08AP9 Q9H8E9 Q08AP8 Q5T2D2 Q8IWY0 |
Accessions | EAX04035 EAX04036 Q5T2D2 AF534824 AAO15022 AJ420509 AK023755 BAB14668 AY358171 AAQ88538 BC125078 AAI25079 BC125079 AAI25080 XM_011514917 XP_011513219 NM_024807 NP_079083 |
Function | Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. {ECO:0000269|PubMed:12645956, ECO:0000269|PubMed:18650384}. |
TREML2 CRISPR/Cas9 KO Plasmid (h) - sc-413276 from Santa Cruz Biotechnology
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TREML2 HDR Plasmid (h) - sc-413276-HDR from Santa Cruz Biotechnology
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TREML2 Double Nickase Plasmid (h) - sc-413276-NIC from Santa Cruz Biotechnology
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TREML2 Double Nickase Plasmid (h2) - sc-413276-NIC-2 from Santa Cruz Biotechnology
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TREML2 CRISPR Activation Plasmid (h) - sc-413276-ACT from Santa Cruz Biotechnology
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TREML2 CRISPR Activation Plasmid (h2) - sc-413276-ACT-2 from Santa Cruz Biotechnology
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TREML2 Lentiviral Activation Particles (h) - sc-413276-LAC from Santa Cruz Biotechnology
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TREML2 Lentiviral Activation Particles (h2) - sc-413276-LAC-2 from Santa Cruz Biotechnology
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TREML2 siRNA (h) - sc-95293 from Santa Cruz Biotechnology
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TREML2 shRNA Plasmid (h) - sc-95293-SH from Santa Cruz Biotechnology
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TREML2 shRNA (h) Lentiviral Particles - sc-95293-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU050871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21940 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21940 from Sigma-Aldrich
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TREML2 siRNA (Human) - CRJ2623 from Cohesion Biosciences
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TREML2 - MBS8212563 from MyBioSource
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shRNA set against Human TREML2 (NM_024807.2) - SHH434188 from Creative biogene
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Human TREML2 siRNA - orb273124 from Biorbyt
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TREML2 shRNA Plasmid (Human) - CHJ2623 from Cohesion Biosciences
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TREML2 miRNA 3'UTR clone - MiUTR4H-TG09328 from Creative biogene
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