UBD

Gene Symbol	UBD
Entrez Gene	10537
Alt Symbol	FAT10, GABBR1, UBD-3
Species	Human
Gene Type	protein-coding
Description	ubiquitin D
Other Description	diubiquitin|ubiquitin-like protein FAT10
Swissprots	O15205 Q5STL2 B0UZT6 Q96EC7 Q5SUK2
Accessions	CAA21458 EAX03201 O15205 AA878968 AF123050 AAD52982 AK311914 BAG34855 BC012472 AAH12472 CB111380 DB181897 DQ894624 ABM85550 Y12653 CAA73200 NM_006398 NP_006389
Function	Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization
Subcellular Location	Nucleus {ECO:0000269|PubMed:12730673, ECO:0000269|PubMed:19033385}. Cytoplasm {ECO:0000250}. Note=Accumulates in aggresomes under proteasome inhibition conditions.
Tissue Specificity	Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in the reticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland. {ECO:0000269|PubMed:12730673, ECO:0000269|PubMed:9368598}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FAT10 / UBD ELISA Kit (Sandwich ELISA) - LS-F4934 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 1.34 ng/ml Range 3.13-200 ng/ml

Ubiquitin D, UBD, Human, ELISA Kit - E-EL-H1253 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Ubiquitin D (UBD), Human, ELISA Kit - SEB744Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 1.34ng/mL Range 3.12-200ng/mL

Ubiquitin D, UBD, Human, ELISA Kit - E1744h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Ubiquitin D, UBD, Rabbit, ELISA Kit - E-EL-RB0214 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ubiquitin D, UBD, Chicken, ELISA Kit - E-EL-Ch1045 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Ubiquitin D, UBD, Porcine, ELISA Kit - E-EL-P1333 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ubiquitin D, UBD, Sheep, ELISA Kit - E-EL-S0941 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Ubiquitin D, UBD, Monkey, ELISA Kit - E-EL-MK1537 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

UBD (Human) Matched Antibody Pair - H00010537-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Ubiquitin D, ELISA Kit - MBS062041 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin D, ELISA Kit - MBS064672 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin D, ELISA Kit - MBS108493 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin D (UBD), ELISA Kit - MBS9307244 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin D (UBD), ELISA Kit - MBS2019707 from MyBioSource Category ELISA Kit Prices $355.00, $540.00, $730.00, $2,985.00, $5,410.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 1.34ng/mL. Range 3.13-200ng/mL

Human UBD(Ubiquitin D) ELISA Kit - E-EL-H1253 from Elabscience Category ELISA Kit Sensitivity 1.88 ng/mL Range 3.13—200 ng/mL

Human UBD (Ubiquitin D) CLIA Kit - E-CL-H0813 from Elabscience Category CLIA Kit Sensitivity 0.47 ng/mL Range Average Recovery (%)

UBD, ELISA Kit - MBS2515201 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

UBD, ELISA Kit - MBS2515495 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875ng/mL Range 3.125--200ng/mL

UBD, ELISA Kit - MBS2505006 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875ng/mL Range 3.125-200ng/mL

UBD, ELISA Kit - MBS2512033 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125-8000pg/mL

UBD, ELISA Kit - MBS2503404 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.875ng/mL Range 3.125-200ng/mL

UBD, ELISA Kit - MBS2510333 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

Ubiquitin D, ELISA Kit - MBS056333 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin D, ELISA Kit - MBS058125 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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