DNMT3L

Gene Symbol	DNMT3L
Entrez Gene	29947
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	DNA (cytosine-5-)-methyltransferase 3-like
Other Description	DNA (cytosine-5)-methyltransferase 3-like|cytosine-5-methyltransferase 3-like protein|human cytosine-5-methyltransferase 3-like protein
Swissprots	Q9BUJ4 Q9UJW3 E9PB42
Accessions	BAA95556 CBH19273 EAX09445 Q9UJW3 AF194032 AAF05812 BC002560 AAH02560 BQ028660 DQ892177 ABM83103 DQ895372 ABM86298 XM_011529536 XP_011527838 NM_013369 NP_037501 NM_175867 NP_787063
Function	Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. {ECO:0000269|PubMed:17687327}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed at low levels in several tissues including testis, ovary, and thymus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNMT3L 293T Cell Transient Overexpression Lysate(Denatured) - H00029947-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DNMT3L overexpression lysate - LY402250 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DNMT3L overexpression lysate - LY406188 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DNMT3L 293 Cell Lysate - 401975 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

DNMT3L 293 Cell Lysate - 403838 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Dnmt3L Overexpression Lysate (Native) - NBL1-09972 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Dnmt3L Overexpression Lysate (Native) - NBL1-09971 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

DNMT3L Over-expression Lysate Product - GWB-9E4E4C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

DNMT3L Over-expression Lysate Product - GWB-287090 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Dnmt3L Overexpression Lysate (Denatured) - H00029947-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Dnmt3L Overexpression Lysate (Denatured) - H00029947-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human DNMT3L Knockdown Stable Cell Line - CSC-DC004465 from Creative biogene Category Cell Line Species Human

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