DNMT3L

Gene Symbol	DNMT3L
Entrez Gene	29947
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	DNA (cytosine-5-)-methyltransferase 3-like
Other Description	DNA (cytosine-5)-methyltransferase 3-like|cytosine-5-methyltransferase 3-like protein|human cytosine-5-methyltransferase 3-like protein
Swissprots	Q9BUJ4 Q9UJW3 E9PB42
Accessions	BAA95556 CBH19273 EAX09445 Q9UJW3 AF194032 AAF05812 BC002560 AAH02560 BQ028660 DQ892177 ABM83103 DQ895372 ABM86298 XM_011529536 XP_011527838 NM_013369 NP_037501 NM_175867 NP_787063
Function	Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. {ECO:0000269|PubMed:17687327}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed at low levels in several tissues including testis, ovary, and thymus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Dnmt3L full length protein - ab170406 from Abcam Category Protein Prices $352.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human Dnmt3L full length protein - ab131960 from Abcam Category Protein Source Wheat germ Species Human

Human Dnmt3L full length protein - ab180335 from Abcam Category Protein Source E. coli Species Human

Human Dnmt3L protein fragment - ab112413 from Abcam Category Protein Source Wheat germ Species Human

Human Dnmt3L protein fragment - ab176954 from Abcam Category Protein Source E. coli Species Human

DNMT3L Antibody Blocking Peptide - LS-E199 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNMT3L Antibody Blocking Peptide - LS-E356 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNMT3L Antibody Blocking Peptide - LS-E4287 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Dnmt3L Partial Recombinant Protein - H00029947-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Dnmt3L Recombinant Protein - H00029947-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Dnmt3L Peptide - P0170 from Novus Biologicals Category Peptide Species Human

Dnmt3L-Antibody-C-term-Blocking-Peptide - BP1040a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DNMT3L-Antibody-C-term-Blocking-Peptide - BP16566b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DNMT3L protein (His tag) - 80R-3767 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

DNMT3L protein (His tag) - 80R-3829 from Fitzgerald Category Protein Prices $375.00 Sizes 50 µg Source E.coli

DNMT3L (1-387, His-tag) - AR51454PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

DNMT3L (1-387, His-tag) - AR51454PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

DNMT3L (1-386, His-tag) - AR51516PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

DNMT3L (1-386, His-tag) - AR51516PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

DNMT3L - H00029947-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DNMT3L - H00029947-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DNMT3L - H00029947-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DNMT3L - H00029947-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DNMT3L, 1-386aa, Human, His tag, E.coli - 01-P2696 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

DNMT3L, 1-387aa, Human, His tag, E.coli - 01-P2634 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

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