DNMT3L

Gene Symbol DNMT3L
Entrez Gene 29947
Alt Symbol -
Species Human
Gene Type protein-coding
Description DNA (cytosine-5-)-methyltransferase 3-like
Other Description DNA (cytosine-5)-methyltransferase 3-like|cytosine-5-methyltransferase 3-like protein|human cytosine-5-methyltransferase 3-like protein
Swissprots Q9BUJ4 Q9UJW3 E9PB42
Accessions BAA95556 CBH19273 EAX09445 Q9UJW3 AF194032 AAF05812 BC002560 AAH02560 BQ028660 DQ892177 ABM83103 DQ895372 ABM86298 XM_011529536 XP_011527838 NM_013369 NP_037501 NM_175867 NP_787063
Function Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. {ECO:0000269|PubMed:17687327}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed at low levels in several tissues including testis, ovary, and thymus.

Dnmt3L CRISPR/Cas9 KO Plasmid (h) - sc-403892 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L HDR Plasmid (h) - sc-403892-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L Double Nickase Plasmid (h) - sc-403892-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L Double Nickase Plasmid (h2) - sc-403892-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L CRISPR Activation Plasmid (h) - sc-403892-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L CRISPR Activation Plasmid (h2) - sc-403892-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L Lentiviral Activation Particles (h) - sc-403892-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L Lentiviral Activation Particles (h2) - sc-403892-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dnmt3L siRNA (h) - sc-37761 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dnmt3L shRNA Plasmid (h) - sc-37761-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dnmt3L shRNA (h) Lentiviral Particles - sc-37761-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dnmt3L RNAi - H00029947-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Dnmt3L RNAi - H00029947-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7407 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7407 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DNMT3L siRNA (Human) - CRH9289 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNMT3L - MBS8212962 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DNMT3L (NM_013369.3) - SHH280037 from Creative biogene

Category siRNA
Species Reactivities Human

DNMT3L shRNA Plasmid (Human) - CHH9289 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DNMT3L miRNA 3'UTR clone - MiUTR4H-TG02818 from Creative biogene

Species Reactivities Human
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