DYRK3

Gene Symbol	DYRK3
Entrez Gene	8444
Alt Symbol	DYRK5, RED, REDK, hYAK3-2
Species	Human
Gene Type	protein-coding
Description	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Other Description	dual specificity tyrosine-phosphorylation-regulated kinase 3|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5|protein kinase Dyrk3|regulatory erythroid kinase
Swissprots	Q7Z752 O43781 Q9HBY7 Q9HBY6 D3DT79
Accessions	EAW93533 EAW93534 EAW93535 O43781 AF186773 AAG17028 AF186774 AAG17029 AF327561 AAK16443 AK291189 BAF83878 AK308082 AK313245 BAG36056 AU126055 AY590695 AAT06103 BC015501 AAH15501 BC037269 AAH37269 JF432389 ADZ15606 Y12735 CAA73266 XM_005273315 XP_005273372 XM_005273316 XP_005273373 XM_006711576 XP_006711639 XM_011510060 XP_011508362 XM_011510061 XP_011508363 NM_001004023 NP_001004023 NM_003582 NP_003573
Function	Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling. {ECO:0000269|PubMed:10779429}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10779429}.
Tissue Specificity	Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus. {ECO:0000269|PubMed:10779429}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human DYRK3 protein fragment - ab135222 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Human DYRK3 full length protein - ab160031 from Abcam Category Protein Source Wheat germ Species Human

Human DYRK3 protein fragment - ab160032 from Abcam Category Protein Source Wheat germ Species Human

DYRK3 Antibody Blocking Peptide - LS-E10673 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DYRK3 Antibody Blocking Peptide - LS-E10672 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DYRK3 Antibody Blocking Peptide - LS-E9032 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DYRK3 Protein - H00008444-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DYRK3 Partial Recombinant Protein - H00008444-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DYRK3 Peptide - P2542 from Novus Biologicals Category Peptide Species Human

DYRK3-Antibody-N-term-Blocking-Peptide - BP7535a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human DYRK3 His GST tag protein - orb84098 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 20 μg, 50 μg Source Insect Species Human

DYRK3 - H00008444-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DYRK3 - H00008444-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DYRK3 - H00008444-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DYRK3 - H00008444-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DYRK3 - P5542 from Acris Antibodies Category Protein Prices $1,010.00 Sizes 5 µg Species Human

DYRK3 fusion protein - ag5249 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

DYRK3 fusion protein - ag5620 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DYRK3, His & GST tagged - DYRK3-972H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

DYRK3 - PN201497 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Baculovirus Species Human

Recombinant Human Dual specificity tyrosine-phosphorylation-regulated kinase 3(DYRK3) - CSB-YP007312HU CSB-EP007312HU CSB-BP007312HU CSB-MP007312HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DYRK3 - H00008444-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Source in vitro transl. Species Human

Human DYRK3 / REDK Protein (His & GST Tag) - 10726-H20B-20 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human DYRK3 / REDK Protein (His & GST tag) - PKSH030392 from Elabscience Category Protein Source Baculoviru Species Human

DYRK3 Peptide, Human - M34GP04655H from Creative Peptides Category Peptide Source Synthetic. Species Human

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