DYRK3

Gene Symbol DYRK3
Entrez Gene 8444
Alt Symbol DYRK5, RED, REDK, hYAK3-2
Species Human
Gene Type protein-coding
Description dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Other Description dual specificity tyrosine-phosphorylation-regulated kinase 3|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5|protein kinase Dyrk3|regulatory erythroid kinase
Swissprots Q7Z752 O43781 Q9HBY7 Q9HBY6 D3DT79
Accessions EAW93533 EAW93534 EAW93535 O43781 AF186773 AAG17028 AF186774 AAG17029 AF327561 AAK16443 AK291189 BAF83878 AK308082 AK313245 BAG36056 AU126055 AY590695 AAT06103 BC015501 AAH15501 BC037269 AAH37269 JF432389 ADZ15606 Y12735 CAA73266 XM_005273315 XP_005273372 XM_005273316 XP_005273373 XM_006711576 XP_006711639 XM_011510060 XP_011508362 XM_011510061 XP_011508363 NM_001004023 NP_001004023 NM_003582 NP_003573
Function Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling. {ECO:0000269|PubMed:10779429}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10779429}.
Tissue Specificity Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus. {ECO:0000269|PubMed:10779429}.

Dyrk3 (D-17) - sc-31975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dyrk3 (D-17): sc-31975. Western blot analysis of Dyrk3 expression in Jurkat whole cell lysate.

Dyrk3 (H-11) - sc-390532 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dyrk3 (H-11): sc-390532. Western blot analysis of Dyrk3 expression in Jurkat whole cell lysate.

Dyrk3 (L-14) - sc-31976 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dyrk3 (H-80) - sc-66868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Dyrk3 (H-80): sc-66868. Western blot analysis of Dyrk3 expression in human spleen (A) and mouse spleen (B) tissue extracts.

Dyrk3 (P-19) - sc-18954 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dyrk3 (P-19): sc-18954. Western blot analysis of Dyrk3 expression in 293T whole cell lysate.

Anti-DYRK3 antibody - ab96617 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DYRK3 antibody (ab96617) at 1/1000 dilution + Raji whole cell lyaste at 30 µg

Anti-DYRK3 antibody - ab104405 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DYRK3 antibody (ab104405) at 1 µg/ml + THP1 cell lysate at 10 µg

Anti-DYRK3 antibody [EPR6078(2)] - ab155949 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6078(2)
All lanes : Anti-DYRK3 antibody [EPR6078(2)] (ab155949) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : THP1 cell lysateLane 3 : HeLa cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-DYRK3 antibody - N-terminal - ab72077 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DYRK3 antibody - N-terminal (ab72077) at 1/1000 dilution + Jurkat cell lysate at 12.5 µgSecondaryHRP-anti-rabbit

Anti-DYRK3 Antibody (clone 3E10) - LS-C105063 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E10

Anti-DYRK3 Antibody (N-Terminus, AP) - LS-C276961 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (N-Terminus, APC) - LS-C276959 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (N-Terminus, Biotin) - LS-C276962 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (N-Terminus, FITC) - LS-C276963 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (N-Terminus, Azide-free, HRP) - LS-C276964 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (N-Terminus, PE) - LS-C276965 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (N-Terminus) - LS-C327245 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DYRK3 Antibody (aa35-84) - LS-C115958 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DYRK3 antibody LS-C115958 Western blot of HT1080 cell lysate.

Anti-DYRK3 Antibody (aa1-30) - LS-C99893 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-DYRK3 antibody in Jurkat cell lysate. DYRK3 (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Anti-DYRK3 Antibody (aa71-120) - LS-C115959 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DYRK3 antibody LS-C115959 Western blot of THP-1 cell lysate.

Anti-DYRK3 Antibody (Internal) - LS-C141513 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of DYRK3 in Jurkat nuclear extracts.

Anti-DYRK3 Antibody (aa243-532) - LS-C185919 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. DYRK3 antibody diluted at 1:1000.

DYRK3 Antibody (563518) - MAB5409 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 563518
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, HepG2 human hepatocellular carcinoma cell line, NIH‑3T3 mouse embryonic fibroblast cell line, and Rat‑2 rat embryonic fibroblast cell line. PVDF Membrane was probed with 2 µg/mL of Mouse Anti-Human/Mouse/Rat DYRK3 Monoclonal Antibody (Catalog # MAB5409) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). Specific bands were detected for DYRK3 at approximately 70 kDa and 72 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

DYRK3 Antibody - AF5409 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of HUVEC human umbilical vein endothelial cells, C2C12 mouse myoblast cell line, L6 rat myoblast cell line, and Rat‑2 rat embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Human/Mouse/Rat DYRK3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5409) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for DYRK3 at approximately 72 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

DYRK3 Antibody - NB110-94876 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DYRK3 Antibody [NB110-94876] - Detection of DYRK3 in Jurkat nuclear extracts using NB110-94876.
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