FBXL3

Gene Symbol FBXL3
Entrez Gene 26224
Alt Symbol FBL3, FBL3A, FBXL3A
Species Human
Gene Type protein-coding
Description F-box and leucine-rich repeat protein 3
Other Description F-box and leucine-rich repeat protein 3A|F-box protein Fbl3a|F-box/LRR-repeat protein 3|F-box/LRR-repeat protein 3A
Swissprots Q9P122 B2RB04 Q9UKT7
Accessions EAW80563 Q9UKT7 AF126028 AAF37383 AF129532 AAF04466 AI133484 AK025484 AK314442 BAG37051 AL833187 BC063796 BC072448 AAH72448 DA119701 HQ447499 ADQ31985 XM_005266336 XP_005266393 XM_005266337 XP_005266394 XM_011535036 XP_011533338 XM_011535037 XP_011533339 NM_012158 NP_036290
Function Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex. {ECO:0000269|PubMed:17463251, ECO:0000269|PubMed:23452855}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10531035}. Cytoplasm {ECO:0000269|PubMed:10531035}. Note=Predominantly nuclear.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10531035}.
Top Pathways Circadian rhythm

Mouse FBXL3 ELISA Kit (Sandwich ELISA) - LS-F7307 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 0.059 ng/ml
Range 0.156-10 ng/ml

F-box/LRR-repeat protein 3 (FBXL3), Human, ELISA Kit - E01F0324 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 1.0pg/ml
Range 50-1000 pg/ml

F box/LRR repeat protein 3 (FBXL3), ELISA Kit - MBS7210985 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box And Leucine Rich Repeat Protein 3 (FBXL3), ELISA Kit - MBS2023777 from MyBioSource

Category ELISA Kit
Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.059ng/mL.
Range 0.156-10ng/mL

ELISA Kit for F-Box And Leucine Rich Repeat Protein 3 (FBXL3) - SEJ121Mu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human FBXL3 ELISA Kit - E013991 from Biobool

Category ELISA Kit

anti-FBXL3 antibody - ARG64064 from Arigo Biolaboratories

Category ELISA Kit

F-Box and Leucine Rich Repeat Protein 3 (FBXL3), ELISA Kit - MBS9372263 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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