PBK

Gene Symbol	PBK
Entrez Gene	55872
Alt Symbol	CT84, HEL164, Nori-3, SPK, TOPK
Species	Human
Gene Type	protein-coding
Description	PDZ binding kinase
Other Description	MAPKK-like protein kinase|T-LAK cell-originated protein kinase|cancer/testis antigen 84|epididymis luminal protein 164|lymphokine-activated killer T-cell-originated protein kinase|serine/threonine protein kinase|spermatogenesis-related protein kinase
Swissprots	Q96KB5 B4DX68 Q9NPD9 Q9NZK6 Q9NYL7 D3DST2
Accessions	CAD43677 EAW63536 EAW63537 Q96KB5 AB027249 BAA99576 AB027250 BAA99577 AF189722 AAF69107 AF237709 AAF71521 AK027291 BAB55019 AK301836 BAG63280 BC015191 AAH15191 BI461026 DB028500 DQ893142 ABM84068 DQ896427 ABM87426 EU794685 ACJ13739 XM_006716368 XP_006716431 NM_001278945 NP_001265874 NM_018492 NP_060962
Function	Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. {ECO:0000269|PubMed:10781613, ECO:0000269|PubMed:17482142}.
Tissue Specificity	Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules. {ECO:0000269|PubMed:10781613, ECO:0000269|PubMed:11378444}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PBK CRISPR/Cas9 KO Plasmid (h) - sc-404069 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK HDR Plasmid (h) - sc-404069-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK Double Nickase Plasmid (h) - sc-404069-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK Double Nickase Plasmid (h2) - sc-404069-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK CRISPR Activation Plasmid (h) - sc-404069-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK CRISPR Activation Plasmid (h2) - sc-404069-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK Lentiviral Activation Particles (h) - sc-404069-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK Lentiviral Activation Particles (h2) - sc-404069-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PBK siRNA (h) - sc-106892 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PBK shRNA Plasmid (h) - sc-106892-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PBK shRNA (h) Lentiviral Particles - sc-106892-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU050111 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1526 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1527 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1528 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN16379 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16379 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06156 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr06156

PBK siRNA (Human) - CRJ0986 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PBK RNAi - H00055872-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PBK (NM_018492.2) - SHH371220 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PBK(NM_018492.2) - SHR090258 from Creative biogene Category siRNA Species Reactivities Human

PBK shRNA Plasmid (Human) - CHJ0986 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PBK miRNA 3'UTR clone - MiUTR1H-07545 from Creative biogene Species Reactivities Human

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