FBXO5

Gene Symbol	FBXO5
Entrez Gene	26271
Alt Symbol	EMI1, FBX5, Fbxo31
Species	Human
Gene Type	protein-coding
Description	F-box protein 5
Other Description	F-box only protein 5|F-box protein Fbx5|early mitotic inhibitor 1
Swissprots	B3KNX5 Q9UGC8 Q8WV29 Q9UKT4 Q5TF47
Accessions	EAW47718 EAW47719 EAW47720 Q9UKT4 AF129535 AAF04469 AJ420499 AK026197 AK055221 BAG51487 AK314456 BAG37064 AY079515 AAL86610 BC018905 AAH18905 BG944882 BI838832 DB122061 DQ891922 ABM82848 DQ895106 ABM86032 XM_011535749 XP_011534051 NM_001142522 NP_001135994 NM_012177 NP_036309
Function	Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding. {ECO:0000269|PubMed:11988738, ECO:0000269|PubMed:16921029}.
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle.
Top Pathways	Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FBXO5-Over-expression-Lysate - LY13422a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

FBXO5 overexpression lysate - LY402160 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

FBXO5 293 Cell Lysate - 401908 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

EMI1 Overexpression Lysate (Native) - NBL1-10639 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

FBXO5 Over-expression Lysate Product - GWB-AF2768 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human FBXO5 Knockdown Stable Cell Line - CSC-DC005616 from Creative biogene Category Cell Line Species Human

Search more