FBXO5

Gene Symbol FBXO5
Entrez Gene 26271
Alt Symbol EMI1, FBX5, Fbxo31
Species Human
Gene Type protein-coding
Description F-box protein 5
Other Description F-box only protein 5|F-box protein Fbx5|early mitotic inhibitor 1
Swissprots B3KNX5 Q9UGC8 Q8WV29 Q9UKT4 Q5TF47
Accessions EAW47718 EAW47719 EAW47720 Q9UKT4 AF129535 AAF04469 AJ420499 AK026197 AK055221 BAG51487 AK314456 BAG37064 AY079515 AAL86610 BC018905 AAH18905 BG944882 BI838832 DB122061 DQ891922 ABM82848 DQ895106 ABM86032 XM_011535749 XP_011534051 NM_001142522 NP_001135994 NM_012177 NP_036309
Function Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding. {ECO:0000269|PubMed:11988738, ECO:0000269|PubMed:16921029}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle.
Top Pathways Oocyte meiosis

Emi1 (B-3) - sc-365212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Emi1 (B-3): sc-365212. Western blot analysis of Emi1 expression in K-562 whole cell lysate.

Emi1 (C-21) - sc-23269 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Emi1 (C-21): sc-23269. Western blot analysis of Emi1 expression in K-562 whole cell lysate.

Emi1 (E-19) - sc-50928 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Emi1 (E-19): sc-50928. Western blot analysis of Emi1 expression in Hep G2 whole cell lysate.

Emi1 (H-300) - sc-30182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Emi1 (H-300): sc-30182. Western blot analysis of Emi1 expression in K-562 whole cell lysate.

Emi1 (N-16) - sc-23267 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Emi1 (N-16): sc-23267. Western blot analysis of Emi1 expression in Hep G2 (A), HEK293 (B), JAR (C), A549 (D) and JEG-3 (E) whole cell lysates and HeLa nuclear extract (F).

Anti-Emi1 antibody - ab129905 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Emi1 antibody (ab129905) at 1/100 dilution + ZR-75-1 cell line lysate at 35 µg

Anti-Emi1 antibody - ab177080 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Emi1 antibody (ab177080) at 1/1000 dilution + A549 whole cell lysate

Anti-Emi1 antibody - ab196273 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Anti-Emi1 antibody (ab196273) at 1/1000 dilution + A549 cell lysate

Anti-Emi1 antibody [EPR15320] - ab184950 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15320
All lanes : Anti-Emi1 antibody [EPR15320] (ab184950) at 1/5000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : 293 cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Emi1 antibody [EPR15320-103] - ab187144 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15320-103
All lanes : Anti-Emi1 antibody [EPR15320-103] (ab187144) at 1/10000 dilutionLane 1 : Hela cell lysateLane 2 : 293 cell lysateLane 3 : HepG2 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-FBXO5 / EMI1 Antibody (aa191-221, AP) - LS-C235243 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa191-221, Biotin) - LS-C235244 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa191-221, FITC) - LS-C235246 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa191-221, APC) - LS-C235245 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa191-221, Azide-free, HRP) - LS-C249977 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa191-221, PE) - LS-C235247 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa326-375) - LS-C80548 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-FBXO5 / EMI1 Antibody (aa358-447) - LS-C307982 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal

Anti-FBXO5 / EMI1 Antibody (aa191-221) - LS-C321327 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO5 / EMI1 Antibody (aa192-221) - LS-C166090 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FBXO5 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The FBXO5 antibody detected the FBXO5 protein (arrow).

EMI1 Antibody - NBP1-84850 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EMI1 Antibody [NBP1-84850] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

FBXO31 Antibody (1H1) - NBP2-01508 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H1

FBXO31 Antibody - NBP1-83916 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FBXO31 Antibody [NBP1-83916] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-214

EMI1 Antibody - NBP1-55050 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EMI1 Antibody [NBP1-55050] - Sample Type: Human Fetal Lung Antibody Dilution: 1.0 ug/ml

EMI1 Antibody (5H7) - H00026271-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 5H7
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