FBXO5

Gene Symbol FBXO5
Entrez Gene 26271
Alt Symbol EMI1, FBX5, Fbxo31
Species Human
Gene Type protein-coding
Description F-box protein 5
Other Description F-box only protein 5|F-box protein Fbx5|early mitotic inhibitor 1
Swissprots B3KNX5 Q9UGC8 Q8WV29 Q9UKT4 Q5TF47
Accessions EAW47718 EAW47719 EAW47720 Q9UKT4 AF129535 AAF04469 AJ420499 AK026197 AK055221 BAG51487 AK314456 BAG37064 AY079515 AAL86610 BC018905 AAH18905 BG944882 BI838832 DB122061 DQ891922 ABM82848 DQ895106 ABM86032 XM_011535749 XP_011534051 NM_001142522 NP_001135994 NM_012177 NP_036309
Function Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding. {ECO:0000269|PubMed:11988738, ECO:0000269|PubMed:16921029}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle.
Top Pathways Oocyte meiosis

Emi1 CRISPR/Cas9 KO Plasmid (h) - sc-405180 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 HDR Plasmid (h) - sc-405180-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 Double Nickase Plasmid (h) - sc-405180-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 Double Nickase Plasmid (h2) - sc-405180-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 CRISPR Activation Plasmid (h) - sc-405180-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 CRISPR Activation Plasmid (h2) - sc-405180-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 Lentiviral Activation Particles (h) - sc-405180-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 Lentiviral Activation Particles (h2) - sc-405180-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emi1 siRNA (h) - sc-37611 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Emi1 shRNA Plasmid (h) - sc-37611-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Emi1 shRNA (h) Lentiviral Particles - sc-37611-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EMI1 RNAi - H00026271-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU019001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8565 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8565 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05872 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05872

FBXO5 siRNA (Human) - CRH8794 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FBXO5 - MBS8205415 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FBXO5 (NM_012177.3) - SHH293393 from Creative biogene

Category siRNA
Species Reactivities Human

Human FBXO5 siRNA - orb269296 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FBXO5 shRNA Plasmid (Human) - CHH8794 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FBXO5 miRNA 3'UTR clone - MiUTR3H-08133 from Creative biogene

Species Reactivities Human

FBXO5 miRNA 3'UTR clone - MiUTR3H-08134 from Creative biogene

Species Reactivities Human
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