FBXO5

Gene Symbol FBXO5
Entrez Gene 26271
Alt Symbol EMI1, FBX5, Fbxo31
Species Human
Gene Type protein-coding
Description F-box protein 5
Other Description F-box only protein 5|F-box protein Fbx5|early mitotic inhibitor 1
Swissprots B3KNX5 Q9UGC8 Q8WV29 Q9UKT4 Q5TF47
Accessions EAW47718 EAW47719 EAW47720 Q9UKT4 AF129535 AAF04469 AJ420499 AK026197 AK055221 BAG51487 AK314456 BAG37064 AY079515 AAL86610 BC018905 AAH18905 BG944882 BI838832 DB122061 DQ891922 ABM82848 DQ895106 ABM86032 XM_011535749 XP_011534051 NM_001142522 NP_001135994 NM_012177 NP_036309
Function Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding. {ECO:0000269|PubMed:11988738, ECO:0000269|PubMed:16921029}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle.
Top Pathways Oocyte meiosis

Human Emi1 protein fragment - ab161960 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161960 on a 12.5% SDS-PAGE stained with Coomassie Blue.

FBXO31 Antibody Blocking Peptide - LS-E4700 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO31 Antibody Blocking Peptide - LS-E19466 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO31 Antibody Blocking Peptide - LS-E19465 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO31 Blocking Peptide - LS-E27019 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO5 / EMI1 Antibody Blocking Peptide - LS-E4450 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human FBXO31 Protein - H00079791-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human FBXO31 Protein - H00079791-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human EMI1 Protein - H00026271-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

EMI1 Peptide - NBP1-96758 from Novus Biologicals

Category Peptide
Prices $169.00
Sizes 50 µg

FBXO5-Antibody-Center-Blocking-Peptide - BP16765c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Goat anti FBXO31 antibody Immunizing peptide - orb15208 from Biorbyt

Category Peptide
Prices $247.00
Sizes 100 μg
Species Human, Mouse, Rat

FBXO31 Blocking Peptide - 33R-7570 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FBXO31 Blocking Peptide - 33R-9406 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FBXO5 Blocking Peptide - 33R-1541 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FBXO5 - H00026271-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

FBXO5 - H00026271-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

FBXO5 fusion protein - ag1296 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

FBXO5 fusion protein - Ag17870 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human F-box only protein 5(FBXO5) - CSB-YP890922HU CSB-EP890922HU CSB-BP890922HU CSB-MP890922HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

FBXO31 Recombinant Protein Antigen - NBP1-83916PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

EMI1 Recombinant Protein Antigen - NBP1-84850PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

FBXO31 Peptide, Human - M34GP05599H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

FBXO5 Peptide, Human - M34GP05616H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

F-box only protein 5 (FBXO5), Recombinant Protein - MBS1302092 from MyBioSource

Category Protein
Prices $1,225.00, $1,225.00, $1,445.00, $1,445.00, $1,990.00, $1,990.00, $2,455.00, $2,455.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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