EIF4EBP3

Gene Symbol	EIF4EBP3
Entrez Gene	8637
Alt Symbol	4E-BP3, 4EBP3
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E binding protein 3
Other Description	eIF4E-binding protein 3|eukaryotic initiation factor 4E-binding protein 3|eukaryotic translation initiation factor 4E-binding protein 3
Swissprots	O60516
Accessions	EAW62056 O60516 AF038869 AAC39761 BC010881 AAH10881 BC069293 AAH69293 BC073751 AAH73751 NM_003732 NP_003723
Function	Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. {ECO:0000250|UniProtKB:Q13541}.
Tissue Specificity	Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus. {ECO:0000269|PubMed:9593750}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EIF4EBP3 Gene cDNA Clone - orb143007 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

EIF4EBP3 - MBS1276134 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010881

Human EIF4EBP3 cDNA clone(NM_003732.2) - CDFH005813 from Creative Biomart Species Human Accession NM_003732.2

Human EIF4EBP3 ORF Clone(NM_003732.2) - CDCR286354 from Creative Biomart Species Human Accession NM_003732.2

Human EIF4EBP3 ORF Clone(NM_003732.2) - CDCR286355 from Creative Biomart Species Human Accession NM_003732.2

Human EIF4EBP3 ORF Clone(NM_003732.2) - CDCR286356 from Creative Biomart Species Human Accession NM_003732.2

Human 4E-BP3 Gene ORF cDNA clone in cloning vector - HG15088-G from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15088-NF from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, N-His tag - HG15088-NH from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15088-CF from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15088-NM from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, C-His tag - HG15088-CH from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15088-CM from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid - HG15088-UT from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15088-CY from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15088-ACR from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15088-ANR from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15088-NY from Sino Biological Species Human

Human EIF4EBP3 ORF Clone(NM_003732.2) - CDCR286354 from Creative biogene Species Human

Human EIF4EBP3 ORF Clone (BC010881) - CDCS411433 from Creative biogene Species Human Accession O60516

Human EIF4EBP3 ORF clone (BC010881) - CDCB158443 from Creative biogene Species Human

Human EIF4EBP3 cDNA Clone(NM_003732.2) - CDFH005813 from Creative biogene Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15088-ANG from Sino Biological Species Human

Human 4E-BP3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15088-ACG from Sino Biological Species Human

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