EIF4EBP3

Gene Symbol	EIF4EBP3
Entrez Gene	8637
Alt Symbol	4E-BP3, 4EBP3
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4E binding protein 3
Other Description	eIF4E-binding protein 3|eukaryotic initiation factor 4E-binding protein 3|eukaryotic translation initiation factor 4E-binding protein 3
Swissprots	O60516
Accessions	EAW62056 O60516 AF038869 AAC39761 BC010881 AAH10881 BC069293 AAH69293 BC073751 AAH73751 NM_003732 NP_003723
Function	Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. {ECO:0000250|UniProtKB:Q13541}.
Tissue Specificity	Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus. {ECO:0000269|PubMed:9593750}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EIF4EBP3 full length protein - ab160128 from Abcam Category Protein Source Wheat germ Species Human

Human EIF4EBP3 full length protein - ab160129 from Abcam Category Protein Source Wheat germ Species Human

Human EIF4EBP3 full length protein - ab183250 from Abcam Category Protein Source E. coli Species Human

Human EIF4EBP3 protein fragment - ab160130 from Abcam Category Protein Source Wheat germ Species Human

EIF4EBP3 Recombinant Protein - H00008637-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EIF4EBP3 Recombinant Protein - H00008637-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EIF4EBP3 Partial Recombinant Protein - H00008637-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Human EIF4EBP3 protein - orb246336 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

EIF4EBP3 protein (His tag) - 80R-3905 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

4E-BP3 (1-100, His-tag) - AR51592PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

4E-BP3 (1-100, His-tag) - AR51592PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

4E-BP3 - H00008637-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

4E-BP3 - H00008637-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

4E-BP3 - H00008637-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

4E-BP3 - H00008637-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

4E-BP3 - H00008637-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

4E-BP3 - H00008637-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

4E-BP3 - H00008637-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EIF4EBP3 fusion protein - Ag23864 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PGEX-4T Species Human

EIF4EBP3 fusion protein - Ag23855 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET28a Species Human

Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 3(EIF4EBP3) - CSB-YP007565HU CSB-BP007565HU CSB-MP007565HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Eukaryotic translation initiation factor 4E-binding protein 3 - CSB-EP007565HU from Cusabio Category Protein Source E.coli Species Human

EIF4EBP3, 1-100a Human, His tag, E.coli - ATGP2772 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

4E-BP3 - TP310053 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EIF4EBP3 Recombinant Protein Antigen - NBP1-91867PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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