Gene Symbol | MSR1 |
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Entrez Gene | 4481 |
Alt Symbol | CD204, SCARA1, SR-A, SRA, phSR1, phSR2 |
Species | Human |
Gene Type | protein-coding |
Description | macrophage scavenger receptor 1 |
Other Description | macrophage acetylated LDL receptor I and II|macrophage scavenger receptor type III|macrophage scavenger receptor types I and II|scavenger receptor class A member 1|scavenger receptor class A, member 1 |
Swissprots | P21759 D3DSP3 P21757 O60505 Q45F10 |
Accessions | AAZ38715 CCQ77679 EAW63830 EAW63831 EAW63832 EAW63833 EAW63834 P21757 AF037351 AAC09251 AK293217 BAG56756 AK293409 BAG56916 BC063878 AAH63878 D13264 D13265 D90187 BAA14208 D90188 BAA14209 DA995755 HQ447469 ADQ31955 NM_002445 NP_002436 NM_138715 NP_619729 NM_138716 NP_619730 |
Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. {ECO:0000269|PubMed:9548586}. |
Top Pathways | Phagosome |
SR-A (E-10) - sc-374130 from Santa Cruz Biotechnology
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SR-A (C-6) - sc-166140 from Santa Cruz Biotechnology
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SR-A (B-9) - sc-166139 from Santa Cruz Biotechnology
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SR-A (E-5) - sc-166184 from Santa Cruz Biotechnology
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SR-A (H-190) - sc-20660 from Santa Cruz Biotechnology
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SR-A (I-20) - sc-20441 from Santa Cruz Biotechnology
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Anti-Macrophage Scavenger Receptor I antibody - ab93290 from Abcam
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Anti-Macrophage Scavenger Receptor I antibody - ab6417 from Abcam
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Anti-Macrophage Scavenger Receptor I antibody - ab125478 from Abcam
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Anti-Macrophage Scavenger Receptor I antibody - ab55508 from Abcam
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Anti-Macrophage Scavenger Receptor I antibody - ab36998 from Abcam
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Anti-Macrophage Scavenger Receptor I antibody [EPR7536] - ab151707 from Abcam
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Anti-MSR1 / CD204 Antibody (clone 2F8, Biotin) - LS-C188109 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa85-134) - LS-C146255 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody - LS-C192840 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (clone 2G8) - LS-C197707 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa336-364) - LS-C164653 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody - LS-C331767 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 5F9) - LS-C338600 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 2B5) - LS-C336673 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 9B8) - LS-C336697 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 5A6) - LS-C336675 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 1F10) - LS-C336679 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 8B11) - LS-C336698 from LifeSpan Bioscience
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Anti-MSR1 / CD204 Antibody (aa197-451, clone 7H5) - LS-C336700 from LifeSpan Bioscience
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