Gene Symbol | MSR1 |
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Entrez Gene | 4481 |
Alt Symbol | CD204, SCARA1, SR-A, SRA, phSR1, phSR2 |
Species | Human |
Gene Type | protein-coding |
Description | macrophage scavenger receptor 1 |
Other Description | macrophage acetylated LDL receptor I and II|macrophage scavenger receptor type III|macrophage scavenger receptor types I and II|scavenger receptor class A member 1|scavenger receptor class A, member 1 |
Swissprots | P21759 D3DSP3 P21757 O60505 Q45F10 |
Accessions | AAZ38715 CCQ77679 EAW63830 EAW63831 EAW63832 EAW63833 EAW63834 P21757 AF037351 AAC09251 AK293217 BAG56756 AK293409 BAG56916 BC063878 AAH63878 D13264 D13265 D90187 BAA14208 D90188 BAA14209 DA995755 HQ447469 ADQ31955 NM_002445 NP_002436 NM_138715 NP_619729 NM_138716 NP_619730 |
Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. {ECO:0000269|PubMed:9548586}. |
Top Pathways | Phagosome |
MSR1-Over-expression-Lysate - LY12972a from Abgent, a WuXi AppTec company
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MSR1 overexpression lysate - LY403366 from Acris Antibodies
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MSR1 overexpression lysate - LY408527 from Acris Antibodies
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MSR1 overexpression lysate - LY419319 from Acris Antibodies
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MSR1 293 Cell Lysate - 404676 from ABBIOTEC
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MSR1 293 Cell Lysate - 402919 from ABBIOTEC
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MSR1 293 Cell Lysate - 409052 from ABBIOTEC
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SR-AI/MSR Overexpression Lysate (Native) - NBL1-13335 from Novus Biologicals
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SR-AI/MSR Overexpression Lysate (Native) - NBP2-05633 from Novus Biologicals
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SR-A (h2): 293T Lysate - sc-111501 from Santa Cruz Biotechnology
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MSR1 Over-expression Lysate Product - GWB-E68AFD from Genway Biotech
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MSR1 Over-expression Lysate Product - GWB-595015 from Genway Biotech
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MSR1 Over-expression Lysate Product - GWB-4C5F3B from Genway Biotech
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Human MSR1 / SCARA1 / CD204 HEK293 Cell Lysate (WB positive control) - 10427-H07HL-300 from Sino Biological
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SR-AI/MSR Overexpression Lysate (Native) - NBP2-10831 from Novus Biologicals
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Human MSR1 Human Cells Transfected Lysate (positive control) (denatured) - orb173013 from Biorbyt
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Panoply™ Human MSR1 Knockdown Stable Cell Line - CSC-DC009834 from Creative biogene
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