Gene Symbol | MSR1 |
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Entrez Gene | 4481 |
Alt Symbol | CD204, SCARA1, SR-A, SRA, phSR1, phSR2 |
Species | Human |
Gene Type | protein-coding |
Description | macrophage scavenger receptor 1 |
Other Description | macrophage acetylated LDL receptor I and II|macrophage scavenger receptor type III|macrophage scavenger receptor types I and II|scavenger receptor class A member 1|scavenger receptor class A, member 1 |
Swissprots | P21759 D3DSP3 P21757 O60505 Q45F10 |
Accessions | AAZ38715 CCQ77679 EAW63830 EAW63831 EAW63832 EAW63833 EAW63834 P21757 AF037351 AAC09251 AK293217 BAG56756 AK293409 BAG56916 BC063878 AAH63878 D13264 D13265 D90187 BAA14208 D90188 BAA14209 DA995755 HQ447469 ADQ31955 NM_002445 NP_002436 NM_138715 NP_619729 NM_138716 NP_619730 |
Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. {ECO:0000269|PubMed:9548586}. |
Top Pathways | Phagosome |
Active human Macrophage Scavenger Receptor I protein fragment - ab174007 from Abcam
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Human Macrophage Scavenger Receptor I protein fragment - ab112323 from Abcam
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Human Macrophage Scavenger Receptor I protein fragment - ab203525 from Abcam
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Human Macrophage Scavenger Receptor I protein fragment - ab169883 from Abcam
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MSR1 / CD204 Antibody Blocking Peptide - LS-E4639 from LifeSpan Bioscience
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MSR1 / CD204 Antibody Blocking Peptide - LS-E23190 from LifeSpan Bioscience
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SR-AI/MSR Blocking Peptide - NB400-159PEP from Novus Biologicals
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SR-AI/MSR Blocking Peptide - NBP1-00093PEP from Novus Biologicals
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SR-AI/MSR Blocking Peptide - NB100-1560PEP from Novus Biologicals
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SR-AI/MSR Blocking Peptide - NBP1-00092PEP from Novus Biologicals
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SR-AI/MSR Partial Recombinant Protein - H00004481-Q01 from Novus Biologicals
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SR-AI/MSR Recombinant Protein - P5001 from Novus Biologicals
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MSR1-Antibody-C-term-Blocking-Peptide - BP17001b from Abgent, a WuXi AppTec company
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Recombinant Human SR-AI/MSR, CF - 2708-MS-050 from R&D Systems
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MSR1 protein (His tag) - 80R-4172 from Fitzgerald
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CD204 (77-451, His-tag) - AR51859PU-N from Acris Antibodies
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CD204 (77-451, His-tag) - AR51859PU-S from Acris Antibodies
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CD204 - H00004481-Q01-10 from Acris Antibodies
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CD204 - H00004481-Q01-25 from Acris Antibodies
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MSR1 Recombinant Protein - 96-542 from ProSci
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MSR1 fusion protein - ag12318 from Proteintech Group
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MSR1 fusion protein - Ag12284 from Proteintech Group
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Recombinant Human MSR1 - MSR1-30164TH from Creative Biomart
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Recombinant Human MSR1, His tagged - MSR1-872H from Creative Biomart
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Recombinant Macrophage Scavenger Receptor 1 (MSR1) - RPB591Hu01 from Uscn Life Science Inc.
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