ATG4D

Gene Symbol	ATG4D
Entrez Gene	84971
Alt Symbol	APG4-D, APG4D, AUTL4
Species	Human
Gene Type	protein-coding
Description	autophagy related 4D, cysteine peptidase
Other Description	APG4 autophagy 4 homolog D|ATG4 autophagy related 4 homolog D|AUT-like 4 cysteine endopeptidase|autophagin-4|autophagy-related cysteine endopeptidase 4|autophagy-related protein 4 homolog D|cysteine protease ATG4D|cysteine protease involved in autophagy
Swissprots	Q969K0 Q86TL0
Accessions	EAW84116 EAW84117 EAW84118 EAW84119 Q86TL0 AJ312332 CAC85951 AK056210 BAB71121 AK223383 BAD97103 AK294676 BAG57839 AK314712 AK316454 BAH14825 BC007639 AAH07639 BC016845 AAH16845 BC068992 AAH68992 BM671285 HQ447598 ADQ32084 HY063028 JF432562 ADZ15779 XM_006722927 XP_006722990 NM_001281504 NP_001268433 NM_032885 NP_116274 NR_104024 NR_104025
Function	Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Subcellular Location	Cysteine protease ATG4D: Cytoplasm.
Tissue Specificity	Mainly expressed in skeletal muscle and, to a lower extent, in testis. {ECO:0000269|PubMed:12446702}.
Top Pathways	Regulation of autophagy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ATG4D-cDNA-Clone - DC08667 from Abgent, a WuXi AppTec company Prices $190.35 Sizes 10 µg Species Human Accession BC007639

ATG4D - MBS1267274 from MyBioSource Species Human Accession BC068992

ATG4D - MBS1269351 from MyBioSource Species Human Accession BC007639

Human ATG4D Gene cDNA Clone (full-length ORF Clone) - HG15537-G from Sino Biological Species Human Accession BC068992

Human ATG4D Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15537-NF from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15537-CF from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, N-HA tag - HG15537-NY from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15537-NM from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15537-ACG from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15537-CM from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15537-ANG from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid - HG15537-UT from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15537-ACR from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, N-His tag - HG15537-NH from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, C-His tag - HG15537-CH from Sino Biological Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, C-HA tag - HG15537-CY from Sino Biological Species Human

Human ATG4D ORF Clone(NM_032885.4) - CDCR313078 from Creative biogene Species Human

Human ATG4D ORF Clone (BC007639) - CDCS416417 from Creative biogene Species Human Accession Q86TL0

Human ATG4D ORF Clone (BC068992) - CDCS416418 from Creative biogene Species Human Accession Q86TL0

Human ATG4D ORF clone (BC068992) - CDCB158061 from Creative biogene Species Human

Human ATG4D cDNA Clone(NM_032885.4) - CDFG006103 from Creative biogene Species Human

Human APG4 D Gene - orb141917 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human ATG4D Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15537-ANR from Sino Biological Species Human

Search more