ATG4D

Gene Symbol	ATG4D
Entrez Gene	84971
Alt Symbol	APG4-D, APG4D, AUTL4
Species	Human
Gene Type	protein-coding
Description	autophagy related 4D, cysteine peptidase
Other Description	APG4 autophagy 4 homolog D|ATG4 autophagy related 4 homolog D|AUT-like 4 cysteine endopeptidase|autophagin-4|autophagy-related cysteine endopeptidase 4|autophagy-related protein 4 homolog D|cysteine protease ATG4D|cysteine protease involved in autophagy
Swissprots	Q969K0 Q86TL0
Accessions	EAW84116 EAW84117 EAW84118 EAW84119 Q86TL0 AJ312332 CAC85951 AK056210 BAB71121 AK223383 BAD97103 AK294676 BAG57839 AK314712 AK316454 BAH14825 BC007639 AAH07639 BC016845 AAH16845 BC068992 AAH68992 BM671285 HQ447598 ADQ32084 HY063028 JF432562 ADZ15779 XM_006722927 XP_006722990 NM_001281504 NP_001268433 NM_032885 NP_116274 NR_104024 NR_104025
Function	Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Subcellular Location	Cysteine protease ATG4D: Cytoplasm.
Tissue Specificity	Mainly expressed in skeletal muscle and, to a lower extent, in testis. {ECO:0000269|PubMed:12446702}.
Top Pathways	Regulation of autophagy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATG4D full length protein - ab164720 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ATG4D Antibody Blocking Peptide - LS-E995 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATG4D Antibody Blocking Peptide - LS-E4684 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATG4D Antibody Blocking Peptide - LS-E5593 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATG4D Antibody Blocking Peptide - LS-E21539 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ATG4D Antibody Blocking Peptide - LS-E27015 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ATG4D Protein - H00084971-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATG4D Peptide - P1530 from Novus Biologicals Category Peptide Species Human

ATG4D Peptide - P1529 from Novus Biologicals Category Peptide Species Human

ATG4D Peptide - P1528 from Novus Biologicals Category Peptide Species Human

ATG4D-Antibody-N-term-Blocking-peptide - BP11448a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APG4D-Antibody-Center-S341-Blocking-Peptide - BP17051c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APG4D-Antibody-Center-Blocking-Peptide - BP1811b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APG4D-Antibody-N-term-Blocking-Peptide - BP1811a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-ATG4DS467-Antibody-Blocking-peptide - BP3395b from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-ATG4DS341-Antibody-Blocking-peptide - BP3395a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-ATG4DS15-Antibody-Blocking-peptide - BP3394a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

ATG4D blocking peptide - GTX88462-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

ATG4D Blocking Peptide - 33R-1446 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ATG4D Peptide - AC21-1840-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

APG4D / ATG4D - H00084971-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

APG4D / ATG4D - H00084971-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ATG4D Peptide - 8075P from ProSci Category Peptide Species Human

ATG4D Peptide - 42-094P from ProSci Category Peptide

ATG4D fusion protein - Ag10307 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

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