ATG4D

Gene Symbol	ATG4D
Entrez Gene	84971
Alt Symbol	APG4-D, APG4D, AUTL4
Species	Human
Gene Type	protein-coding
Description	autophagy related 4D, cysteine peptidase
Other Description	APG4 autophagy 4 homolog D|ATG4 autophagy related 4 homolog D|AUT-like 4 cysteine endopeptidase|autophagin-4|autophagy-related cysteine endopeptidase 4|autophagy-related protein 4 homolog D|cysteine protease ATG4D|cysteine protease involved in autophagy
Swissprots	Q969K0 Q86TL0
Accessions	EAW84116 EAW84117 EAW84118 EAW84119 Q86TL0 AJ312332 CAC85951 AK056210 BAB71121 AK223383 BAD97103 AK294676 BAG57839 AK314712 AK316454 BAH14825 BC007639 AAH07639 BC016845 AAH16845 BC068992 AAH68992 BM671285 HQ447598 ADQ32084 HY063028 JF432562 ADZ15779 XM_006722927 XP_006722990 NM_001281504 NP_001268433 NM_032885 NP_116274 NR_104024 NR_104025
Function	Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Subcellular Location	Cysteine protease ATG4D: Cytoplasm.
Tissue Specificity	Mainly expressed in skeletal muscle and, to a lower extent, in testis. {ECO:0000269|PubMed:12446702}.
Top Pathways	Regulation of autophagy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Atg4D (C-14) - sc-138835 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Atg4D (E-20) - sc-138836 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Atg4D (T-15) - sc-138837 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-ATG4D antibody - ab137621 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D antibody - ab64734 from Abcam Host Rabbit Clonality Polyclonal

Anti-ATG4D antibody - ab64736 from Abcam Host Sheep Clonality Polyclonal

Anti-ATG4D antibody - ab64735 from Abcam Host Sheep Clonality Polyclonal

Anti-ATG4D antibody - ab176870 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATG4D antibody - ab129291 from Abcam Prices $407.00 Sizes 50 µg Host Goat Clonality Polyclonal

Anti-ATG4D antibody - ab130289 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (aa49-79) - LS-C156602 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (N-Terminus) - LS-C190049 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (aa200-249) - LS-C116978 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (clone 222CT15.4.1, AP) - LS-C221248 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 222CT15.4.1

Anti-ATG4D Antibody (clone 222CT15.4.1, APC) - LS-C221250 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 222CT15.4.1

Anti-ATG4D Antibody (clone 222CT15.4.1, Azide-free, HRP) - LS-C221251 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 222CT15.4.1

Anti-ATG4D Antibody (clone 222CT15.4.1, Biotin) - LS-C221252 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 222CT15.4.1

Anti-ATG4D Antibody (clone 222CT15.4.1, PE) - LS-C221254 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 222CT15.4.1

Anti-ATG4D Antibody (clone 222CT15.4.1, FITC) - LS-C221253 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 222CT15.4.1

Anti-ATG4D Antibody (aa320-346, AP) - LS-C221447 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (aa320-346) - LS-C156405 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (aa320-346, APC) - LS-C221448 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody - LS-C156605 from LifeSpan Bioscience Prices $295.00 Sizes 100 µl Host Mouse Clonality Monoclonal

Anti-ATG4D Antibody (aa320-346, Biotin) - LS-C221449 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATG4D Antibody (aa320-346, FITC) - LS-C221450 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Search more