AFAP1

Gene Symbol	AFAP1
Entrez Gene	60312
Alt Symbol	AFAP, AFAP-110, AFAP110
Species	Human
Gene Type	protein-coding
Description	actin filament associated protein 1
Other Description	110 kDa actin filament-associated protein|actin filament-associated protein 1|actin filament-associated protein, 110 kDa
Swissprots	Q59EY5 E9PDT7 B4DMU2 Q8N556 Q9HBY1 A8K442
Accessions	EAW82360 Q8N556 AB209676 BAD92913 AF188700 AAG17055 AK127962 BAC87209 AK290807 BAF83496 AK297631 BAG60004 AL706541 BC015900 BC032777 AAH32777 BI561136 CA448961 CN308844 D25248 DA605903 DB450895 DQ585763 XM_006713908 XP_006713971 XM_006713909 XP_006713972 XM_011513544 XP_011511846 XM_011513545 XP_011511847 XM_011513546 XP_011511848 NM_001134647 NP_001128119 NM_198595 NP_940997 NM_021638
Function	Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. {ECO:0000250, ECO:0000269|PubMed:15485829}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15485829}. Note=Localizes with stress fibers in quiescent cells, concentrated in cell motility structures such as lamellipodia, filopodia and membrane ruffles upon their induction.
Tissue Specificity	Low expression in normal breast epithelial cell line MCF-10A and in tumorigenic breast cancer cell lines MCF- 7, T-47D and ZR-75-1. Highly expressed in the invasive breast cancer cell lines MDA-MB-231 and MDA-MB-435. Overexpressed in prostate carcinoma. {ECO:0000269|PubMed:17520695, ECO:0000269|PubMed:17885682}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Actin Filament Associated Protein 1, AFAP1, Human, ELISA Kit - E-EL-H0286 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

AFAP1 (Actin Filament Associated Protein 1), Rabbit, ELISA Kit - E-EL-RB1019 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

AFAP1 (Actin Filament Associated Protein 1), Chicken, ELISA Kit - E-EL-Ch1447 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

AFAP1 (Actin Filament Associated Protein 1), Pig, ELISA Kit - E-EL-P1276 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

AFAP1 (Actin Filament Associated Protein 1), Guinea Pig, ELISA Kit - E-EL-GP1035 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

AFAP1 (Actin Filament Associated Protein 1), Monkey, ELISA Kit - E-EL-MK1511 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

Human AFAP1 ELISA Kit - HA0590 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine AFAP1 ELISA Kit - AA0590 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human AFAP1(Actin Filament Associated Protein 1) ELISA Kit - E-EL-H0286 from Elabscience Category ELISA Kit Sensitivity 0.47 ng/mL Range 0.78—50 ng/mL

Actin Filament Associated Protein 1, ELISA Kit - MBS746257 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS028433 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS011286 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS019734 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS034838 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS031802 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS018768 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS754262 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS754014 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS062564 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS041836 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS046715 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS055939 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS006819 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS011685 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Actin Filament Associated Protein 1, ELISA Kit - MBS750505 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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