Gene Symbol | TSSK2 |
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Entrez Gene | 23617 |
Alt Symbol | DGS-G, SPOGA2, STK22B, TSK2 |
Species | Human |
Gene Type | protein-coding |
Description | testis-specific serine kinase 2 |
Other Description | TSK-2|TSSK-2|diGeorge syndrome protein G|serine/threonine kinase 22B (spermiogenesis associated)|serine/threonine-protein kinase 22B|spermiogenesis associated 2|testis specific serine threonine kinase 2|testis-specific kinase 2|testis-specific serine/threonine-protein kinase 2 |
Swissprots | Q8IY55 Q96PF2 |
Accessions | BAF41974 CBH30659 EAX03058 Q96PF2 AF362953 AAK98531 BC037781 AAH37781 CR456587 CAG30473 L77564 NM_053006 NP_443732 |
Function | Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. {ECO:0000269|PubMed:15044604, ECO:0000269|PubMed:18533145, ECO:0000269|PubMed:20729278}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:18495105}. Note=Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment (By similarity). In spermatids, concentrates in centrioles during flagellogenesis. {ECO:0000250}. |
Tissue Specificity | Testis-specific. Present in mature spermatozoa (at protein level). {ECO:0000269|PubMed:15044604, ECO:0000269|PubMed:18533145, ECO:0000269|PubMed:20729278}. |
TSSK 2 (H-91) - sc-366940 from Santa Cruz Biotechnology
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TSSK 2 (P-12) - sc-86253 from Santa Cruz Biotechnology
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TSSK 2 (C-19) - sc-86251 from Santa Cruz Biotechnology
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TSSK 2 (S-09) - sc-100437 from Santa Cruz Biotechnology
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Anti-TSSK2 [EPR16116] antibody - ab192026 from Abcam
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Anti-TSSK2 antibody - ab57191 from Abcam
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Anti-TSSK2 antibody - ab172434 from Abcam
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Anti-TSSK2 antibody - ab60218 from Abcam
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Anti-TSSK2 antibody - ab57189 from Abcam
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Anti-TSSK2 antibody - ab98051 from Abcam
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Anti-TSSK2 Antibody (aa251-300) - LS-C107737 from LifeSpan Bioscience
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Anti-TSSK2 Antibody (C-Terminus) - LS-C117258 from LifeSpan Bioscience
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Anti-TSSK2 Antibody (clone 1H2) - LS-C105125 from LifeSpan Bioscience
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TSSK2 Antibody (1E12) - H00023617-M01 from Novus Biologicals
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TSSK2 Antibody (1H2) - H00023617-M02 from Novus Biologicals
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TSSK2 Antibody - NBP1-52968 from Novus Biologicals
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TSSK2 Antibody - H00023617-D01P from Novus Biologicals
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TSSK2 Antibody (1F6) - H00023617-M03 from Novus Biologicals
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TSSK2 Antibody - H00023617-B01 from Novus Biologicals
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Monoclonal Anti-TSSK2, (C-terminal) antibody produced in mouse - SAB1404984 from Sigma-Aldrich
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Anti-TSSK2 antibody produced in rabbit - SAB2104933 from Sigma-Aldrich
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Anti-TSSK2 antibody produced in rabbit - SAB1410437 from Sigma-Aldrich
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Monoclonal Anti-TSSK2 antibody produced in mouse - WH0023617M1 from Sigma-Aldrich
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ANTI-TSSK2 antibody produced in mouse - SAB1412204 from Sigma-Aldrich
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TSSK2 antibody - middle region (ARP53818_P050) - ARP53818_P050 from Aviva Systems Biology
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