TYRP1

Gene Symbol TYRP1
Entrez Gene 7306
Alt Symbol CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN
Species Human
Gene Type protein-coding
Description tyrosinase-related protein 1
Other Description 5,6-dihydroxyindole-2-carboxylic acid oxidase|DHICA oxidase|catalase B|glycoprotein 75|melanoma antigen gp75
Swissprots P78468 Q15679 P78469 P17643 Q13721
Accessions AAC15468 AAC41924 AAR01256 AAR01257 BAA11759 CAA43288 EAW58709 EAW58710 EAW58711 EAW58712 P17643 AK297887 BAG60208 AL600654 BC052608 AAH52608 CD679533 CR407683 CAG28611 DA278582 X51420 CAA35785 X51455 CAA35820 NM_000550 NP_000541
Function Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Subcellular Location Melanosome membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex (By similarity). {ECO:0000250}.
Tissue Specificity Pigment cells.
Top Pathways Melanogenesis, Tyrosine metabolism

Human TYRP1 ORF clone(NM_000550.2) - CDCL186658 from Creative Biomart

Species Human
Accession NM_000550.2

Human TYRP1 ORF clone(NM_000550.2) - CDCR008023 from Creative Biomart

Species Human
Accession NM_000550.2

Human TYRP1 ORF Clone(NM_000550.2) - CDCL180199 from Creative Biomart

Species Human
Accession NM_000550.2

human TYRP1 ORF clone - CDCH097100 from Creative Biomart

Species Human
Accession NM_000550

human TYRP1 ORF clone - CDCH097101 from Creative Biomart

Species Human
Accession NM_000550

human TYRP1 ORF clone - CDCH097102 from Creative Biomart

Species Human
Accession NM_000550

human TYRP1 ORF clone - CDCH097103 from Creative Biomart

Species Human
Accession NM_000550

Human TYRP1 ORF clone(NM_000550.2) - CDCL186658 from Creative biogene

Species Human
Search more