TYRP1

Gene Symbol TYRP1
Entrez Gene 7306
Alt Symbol CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN
Species Human
Gene Type protein-coding
Description tyrosinase-related protein 1
Other Description 5,6-dihydroxyindole-2-carboxylic acid oxidase|DHICA oxidase|catalase B|glycoprotein 75|melanoma antigen gp75
Swissprots P78468 Q15679 P78469 P17643 Q13721
Accessions AAC15468 AAC41924 AAR01256 AAR01257 BAA11759 CAA43288 EAW58709 EAW58710 EAW58711 EAW58712 P17643 AK297887 BAG60208 AL600654 BC052608 AAH52608 CD679533 CR407683 CAG28611 DA278582 X51420 CAA35785 X51455 CAA35820 NM_000550 NP_000541
Function Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Subcellular Location Melanosome membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex (By similarity). {ECO:0000250}.
Tissue Specificity Pigment cells.
Top Pathways Melanogenesis, Tyrosine metabolism

TRP1 (G-9) - sc-166857 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRP1 (G-9): sc-166857. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

TRP1 (H-90) - sc-25543 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRP1 (H-90): sc-25543. Western blot analysis of TRP1 expression in B16-F0 whole cell lysate.

TRP1 (SPM456) - sc-56491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

TRP1 (TA99) - sc-58438 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

TRP1 (F-6) - sc-166791 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRP1 (F-6): sc-166791. Western blot analysis of TRP1 expression in B16-F0 whole cell lysate.

TRP1 (G-17) - sc-10443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRP1 (G-17) Alexa Fluor 647: sc-10443 AF647. Intracellular FCM analysis of fixed and permeabilized B16-FO cells. Black line histogram represents the isotype control, normal goat IgG: sc-45066.

TRP1 (23) - sc-136388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRP1 (23): sc-136388. Western blot analysis of TRP1 expression in SK-MEL5 whole cell lysate.

TRP1 (3F388) - sc-58437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

TRP1 (4D25) - sc-73239 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-TRP1 antibody [3F388] - ab18084 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3F388

Anti-TRP1 antibody [EPR13064(B)] - C-terminal - ab177468 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13064(B)
Immunohistochemical analysis of paraffin-embedded Human melanoma tissue labeling TRP1 with ab177468 at 1/50 diultion.

Anti-TRP1 antibody [G3E6] - ab49684 from Abcam

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone G3E6
ab49684 staining TRP1 in Dog skin tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 5% serum for 30 minutes at 25°C; antigen retrieval was by heat mediation in 10mM citrate, pH 6.0. Samples were incubated with primary antibody (1/50 in PBS + 1x casein) for 1 hour at 37°C. An undiluted HRP-conjugated Hydra vulgaris anti-mouse IgG polyclonal was used as the secondary antibody.See Abreview

Anti-TRP1 antibody [TA99] - ab3312 from Abcam

Prices $392.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone TA99
Anti-TRP1 antibody [TA99] (ab3312) at 5 µg/ml + Skin (Human) Tissue Lysate - adult normal tissue (ab30166) at 20 µgSecondaryGoat polyclonal Secondary Antibody to Mouse IgG - H&L (HRP), pre-adsorbed at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-TRP1 antibody [TA99] - ab190709 from Abcam

Prices $373.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone TA99

Anti-TRP1 antibody [TA99] - ab80781 from Abcam

Prices $372.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone TA99

Anti-TRP1 antibody [Ta99], prediluted - ab11781 from Abcam

Prices $370.00
Sizes 6 ml
Host Mouse
Clonality Monoclonal
Clone Ta99

Anti-Tyrosinase Related Protein 75 antibody [EPR13063] - ab178676 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13063
Anti-Tyrosinase Related Protein 75 antibody [EPR13063] (ab178676) at 1/10000 dilution + Human melanoma lysate at 10 µg

Anti-Tyrosinase Related Protein 75 antibody - ab89635 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Tyrosinase Related Protein 75 antibody (ab89635) at 1 µg/ml + Human pancreas lysate at 50 µg

Anti-TYRP1 / gp75 Antibody (aa340-371, FITC) - LS-C224568 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TYRP1 / gp75 Antibody (aa340-371, Azide-free, HRP) - LS-C224569 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TYRP1 / gp75 Antibody (aa340-371) - LS-C330270 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TYRP1 / gp75 Antibody (aa380-429) - LS-C135160 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TYRP1 /gp75 antibody LS-C135160 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-TYRP1 / gp75 Antibody (aa151-200) - LS-C40470 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
TYRP1 /gp75 antibody LS-C40470 Western blot of Jurkat lysate.

Anti-TYRP1 / gp75 Antibody (aa340-371) - LS-C157304 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TYRP1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The TYRP1 antibody detected the TYRP1 protein (arrow).

Anti-TYRP1 / gp75 Antibody (aa340-371, PE) - LS-C224571 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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