TYRP1

Gene Symbol TYRP1
Entrez Gene 7306
Alt Symbol CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN
Species Human
Gene Type protein-coding
Description tyrosinase-related protein 1
Other Description 5,6-dihydroxyindole-2-carboxylic acid oxidase|DHICA oxidase|catalase B|glycoprotein 75|melanoma antigen gp75
Swissprots P78468 Q15679 P78469 P17643 Q13721
Accessions AAC15468 AAC41924 AAR01256 AAR01257 BAA11759 CAA43288 EAW58709 EAW58710 EAW58711 EAW58712 P17643 AK297887 BAG60208 AL600654 BC052608 AAH52608 CD679533 CR407683 CAG28611 DA278582 X51420 CAA35785 X51455 CAA35820 NM_000550 NP_000541
Function Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Subcellular Location Melanosome membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex (By similarity). {ECO:0000250}.
Tissue Specificity Pigment cells.
Top Pathways Melanogenesis, Tyrosine metabolism

TRP1 CRISPR/Cas9 KO Plasmid (h) - sc-400412 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 HDR Plasmid (h) - sc-400412-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 Double Nickase Plasmid (h) - sc-400412-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 Double Nickase Plasmid (h2) - sc-400412-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 CRISPR Activation Plasmid (h) - sc-400412-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 CRISPR Activation Plasmid (h2) - sc-400412-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 Lentiviral Activation Particles (h) - sc-400412-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 Lentiviral Activation Particles (h2) - sc-400412-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRP1 siRNA (h) - sc-36745 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRP1 shRNA Plasmid (h) - sc-36745-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRP1 shRNA (h) Lentiviral Particles - sc-36745-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU043111 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1743 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1743 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07707 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07707

TYRP1 siRNA (Human) - CRH4996 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TYRP1 - MBS8201668 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TYRP1 (NM_000550.2) - SHH438480 from Creative biogene

Category siRNA
Species Reactivities Human

Human TYRP1 siRNA - orb265498 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TYRP1 shRNA Plasmid (Human) - CHH4996 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TYRP1 miRNA 3'UTR clone - MiUTR3H-00363 from Creative biogene

Species Reactivities Human
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