Gene Symbol | ASCL1 |
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Entrez Gene | 429 |
Alt Symbol | ASH1, HASH1, MASH1, bHLHa46 |
Species | Human |
Gene Type | protein-coding |
Description | achaete-scute family bHLH transcription factor 1 |
Other Description | ASH-1|achaete scute protein|achaete-scute complex homolog 1|achaete-scute complex-like 1|achaete-scute homolog 1|class A basic helix-loop-helix protein 46 |
Swissprots | Q9BQ30 A8K3C4 P50553 |
Accessions | EAW97703 P50553 AK290539 BAF83228 AK314114 AW071836 BC001638 BC002341 AAH02341 BC003134 AAH03134 BC004425 AAH04425 BC031299 AAH31299 CF454566 DA005289 DQ894571 ABM85497 EU176303 ABW03754 L08424 AAA58376 NM_004316 NP_004307 |
Function | Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG- 3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
ASCL1 (G-7) - sc-390794 from Santa Cruz Biotechnology
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ASCL1 (C-16) - sc-13222 from Santa Cruz Biotechnology
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ASCL1 (C-15) - sc-48449 from Santa Cruz Biotechnology
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ASCL1 (D-7) - sc-374104 from Santa Cruz Biotechnology
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ASCL1 (G-9) - sc-374550 from Santa Cruz Biotechnology
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ASCL1 (H-56) - sc-28688 from Santa Cruz Biotechnology
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ASCL1 (N-17) - sc-13219 from Santa Cruz Biotechnology
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Anti-MASH1/Achaete-scute homolog 1 antibody - ab38556 from Abcam
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Anti-MASH1/Achaete-scute homolog 1 antibody - ab135273 from Abcam
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Anti-MASH1/Achaete-scute homolog 1 antibody - ab71197 from Abcam
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Anti-MASH1/Achaete-scute homolog 1 antibody - ab54823 from Abcam
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Anti-ASCL1 / MASH1 Antibody (C-Terminus, FITC) - LS-C275279 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (aa109-158) - LS-C291669 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (C-Terminus) - LS-C326885 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (C-Terminus, Azide-free, HRP) - LS-C275280 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (C-Terminus, PE) - LS-C275284 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (C-Terminus) - LS-C319630 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (aa63-90) - LS-C319635 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody - LS-C309526 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (N-Terminus) - LS-C326882 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody IHC-plus⢠- LS-B9400 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (clone 301733) - LS-C85290 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody (aa36-50) - LS-C87213 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody - LS-C69309 from LifeSpan Bioscience
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Anti-ASCL1 / MASH1 Antibody - LS-C69310 from LifeSpan Bioscience
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