Gene Symbol | ASCL1 |
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Entrez Gene | 429 |
Alt Symbol | ASH1, HASH1, MASH1, bHLHa46 |
Species | Human |
Gene Type | protein-coding |
Description | achaete-scute family bHLH transcription factor 1 |
Other Description | ASH-1|achaete scute protein|achaete-scute complex homolog 1|achaete-scute complex-like 1|achaete-scute homolog 1|class A basic helix-loop-helix protein 46 |
Swissprots | Q9BQ30 A8K3C4 P50553 |
Accessions | EAW97703 P50553 AK290539 BAF83228 AK314114 AW071836 BC001638 BC002341 AAH02341 BC003134 AAH03134 BC004425 AAH04425 BC031299 AAH31299 CF454566 DA005289 DQ894571 ABM85497 EU176303 ABW03754 L08424 AAA58376 NM_004316 NP_004307 |
Function | Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG- 3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human MASH1/Achaete-scute homolog 1 full length protein - ab152200 from Abcam
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Human MASH1/Achaete-scute homolog 1 peptide - ab74622 from Abcam
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Human MASH1/Achaete-scute homolog 1 peptide - ab74623 from Abcam
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Human MASH1/Achaete-scute homolog 1 protein fragment - ab114273 from Abcam
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ASCL1 / MASH1 Antibody Blocking Peptide - LS-E6811 from LifeSpan Bioscience
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ASCL1 / MASH1 Antibody Blocking Peptide - LS-E26413 from LifeSpan Bioscience
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Recombinant Human ASCL1/Mash1 Protein - H00000429-Q01 from Novus Biologicals
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Recombinant Human ASCL1/Mash1 Protein - H00000429-P01 from Novus Biologicals
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ASCL1/Mash1 Peptide - P0814 from Novus Biologicals
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ASCL1/Mash1 Peptide - P0813 from Novus Biologicals
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ASCL1-Achaete-scute-homolog-1-Antibody-C-term-Blocking-peptide - BP2019b from Abgent, a WuXi AppTec company
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ASCL1-Achaete-scute-homolog-1-Antibody-N-term-Blocking-peptide - BP2019a from Abgent, a WuXi AppTec company
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ASCL1 peptide - orb219000 from Biorbyt
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MASH1 Blocking Peptide - abx062031 from Abbexa
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ASCL1 - H00000429-P01 from Acris Antibodies
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ASCL1 - H00000429-Q01-10 from Acris Antibodies
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ASCL1 - H00000429-Q01-25 from Acris Antibodies
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ASCL1 - H00000429-Q03-10 from Acris Antibodies
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ASCL1 - H00000429-Q03-25 from Acris Antibodies
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ASCL1 fusion protein - ag19360 from Proteintech Group
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Recombinant Human ASCL1 - ASCL1-28522TH from Creative Biomart
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Recombinant Achaete Scute Complex Like Protein 1 (ASCL1) - RPJ867Hu01 from Uscn Life Science Inc.
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MASH1 Blocking Peptide - CBP3137 from Cohesion Biosciences
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ASCL1 (E158) Peptide - BS3688P from Bioworld Technology
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Recombinant Achaete Scute Complex Like Protein 1 (ASCL1) - RPJ867Hu01 from Cloud-clone
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