SPRED2

Gene Symbol SPRED2
Entrez Gene 200734
Alt Symbol Spred-2
Species Human
Gene Type protein-coding
Description sprouty-related, EVH1 domain containing 2
Other Description sprouty protein with EVH-1 domain 2, related sequence|sprouty-related, EVH1 domain-containing protein 2
Swissprots D6W5F7 A1L3V4 Q2NKX6 B7Z5K7 Q7Z698 E9PEP0
Accessions EAW99904 EAW99905 EAW99906 Q7Z698 AF052178 AK025550 AK056479 BAG51727 AK299079 BAH12943 AK307714 AY299090 AAP59415 BC029300 BC111495 AAI11496 BC130292 AAI30293 BC136334 AAI36335 DA102390 DC335282 HQ258249 ADR83003 XM_005264200 XP_005264257 XM_005264201 XP_005264258 XM_005264202 XP_005264259 XM_006711966 XP_006712029 NM_001128210 NP_001121682 NM_181784 NP_861449
Function Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase.
Subcellular Location Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm. Note=Especially found in the cytoplasm of the stratum spinosum cells called membrane-coated granules.
Tissue Specificity Expressed in liver, skin, small intestine, salivary gland and prostate. {ECO:0000269|PubMed:15580519}.
Top Pathways Jak-STAT signaling pathway

SPRED2 (T-18) - sc-240921 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SPRED2 (T-18): sc-240921. Western blot analysis of SPRED2 expression in HeLa whole cell lysate.

SPRED2 (H-60) - sc-98291 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SPRED2 antibody - ab50535 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRED2 antibody - ab153700 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human Breast carcinoma tissue labeling SPRED2 with ab153700 at 1/500 dilution.

Anti-SPRED2 antibody - ab58127 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58127 SPRED2 antibody at 1ug/ml.

Anti-SPRED2 Antibody - LS-C190148 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRED2 Antibody (Internal) - LS-C82864 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of Spred2 in human small intestine tissue lysate with Spred2 antibody at (A) 1 and (B) 2 ug/ml

Anti-SPRED2 Antibody (aa317-366) - LS-C135784 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SPRED2 antibody LS-C135784 Western blot of HepG2 cell lysate.

SPRED2 Antibody - AF4819 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of Hep3B human hepatocellular carcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Human SPRED2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4819) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for SPRED2 at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

SPRED2 Antibody - NBP2-20478 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPRED2 Antibody [NBP2-20478] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE gel, diluted at 1:1000.

SPRED2 Antibody (6G8) - H00200734-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6G8
ELISA: SPRED2 Antibody (6G8) [H00200734-M01] - Detection limit for recombinant GST tagged SPRED2 is approximately 1ng/ml as a capture antibody.

SPRED2 Antibody - NBP1-76342 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SPRED2 Antibody [NBP1-76342] - Human small intestine tissue lysate with Spred2 antibody at (A) 1 and (B) 2 ug/mL.

SPRED2 Antibody - H00200734-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

SPRED2 Antibody (2G11) - H00200734-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G11

Monoclonal Anti-SPRED2 antibody produced in mouse - WH0200734M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6G8
<B>Immunoblotting</B><BR/>Monoclonal Anti-SPRED2, <B>Cat. No. WH0200734M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

Anti-Spred2 antibody produced in rabbit - PRS4849 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Spred2: <B>Cat. No. PRS4849</B> Western blot analysis of Spred2 in human small intestine tissue lysate with Spred2 antibody at (A) 1 and (B) 2 μg/mL.

Monoclonal Anti-SPRED2 antibody produced in mouse - SAB1405381 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G11
<B>Immunoblotting</B><BR/>Monoclonal Anti-SPRED2: <B>Cat. No. SAB1405381</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.1 kDa using immunogen protein lysate.

Anti-Spred-2 antibody produced in rabbit - S7320 from Sigma-Aldrich

Prices $403.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

SPRED2 antibody - C-terminal region (ARP60369_P050) - ARP60369_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Human SPRED2 Antibody - AF4819 from R&D Systems

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Sheep
Detection of Human SPRED2 by Western Blot. Western blot shows lysates of Hep3B human hepatocellular carcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Human SPRED2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4819) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). A specific band was detected for SPRED2 at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8 .

Human SPRED2 Affinity Purified Polyclonal Ab, Sheep IgG - AF4819-SP from R&D Systems

Host Sheep
Clonality Polyclonal
Detection of Human SPRED2 by Western Blot. Western blot shows lysates of Hep3B human hepatocellular carcinoma cell line. PVDF Membrane was probed with 1 µg/mL of Human SPRED2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4819) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for SPRED2 at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Spred2 antibody - orb75080 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of human small intestine tissue at (A) 1 and (B) 2 ug/mL using Spred2 antibody

SPRED2 antibody - 70R-10053 from Fitzgerald

Host Rabbit
Clonality Polyclonal

SPRED2 antibody - 24091-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human testis tissue slide using 24091-1-AP( SPRED2 Antibody) at dilution of 1:50 (under 10x lens)

SPRED2 antibody - AP30823PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Spred2 in human small intestine tissue lysate with AP30823PU-N at (A) 1 and (B) 2 μg/ml.
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