PDE2A

Gene Symbol PDE2A
Entrez Gene 5138
Alt Symbol CGS-PDE, PDE2A1, PED2A4, cGSPDE
Species Human
Gene Type protein-coding
Description phosphodiesterase 2A, cGMP-stimulated
Other Description cGMP-dependent 3',5'-cyclic phosphodiesterase|cGMP-stimulated phosphodiesterase 1|cGMP-stimulated phosphodiesterase 4|cyclic GMP-stimulated phosphodiesterase
Swissprots Q5J791 O00408 Q6ZMR1 E9PGI1 B3KRV5 Q5J793 B2R646 F6W5Z0 Q5J792
Accessions CCQ43186 EAW74861 EAW74862 O00408 AI498038 AK092278 BAG52517 AK095024 BAG52972 AK131525 BAD18664 AK295676 BAG58533 AK312434 BAG35343 AY495087 AAS75513 AY495088 AAS75514 AY495089 AAS75515 BC040974 AAH40974 BI760519 DA219662 DA227593 DA243617 DA325165 DA329075 DA332549 DA504595 DA801834 DB068707 U67733 AAC51320 XM_005274040 XP_005274097 XM_011545096 XP_011543398 NM_001143839 NP_001137311 NM_001146209 NP_001139681 NM_001243784 NP_001230713 NM_002599 NP_002590
Function Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Subcellular Location Isoform PDE2A1: Cytoplasm {ECO:0000269|PubMed:19632989}.
Tissue Specificity Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
Top Pathways Morphine addiction, cGMP-PKG signaling pathway, Purine metabolism

PDE2A (G-12) - sc-271394 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE2A (G-12): sc-271394. Western blot analysis of PDE2A expression in IMR-32 whole cell lysate.

PDE2A (H-300) - sc-25565 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PDE2A (H-300): sc-25565. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebral cortex tissue showing cytoplasmic and nuclear staining of neuronal cells and cyoplasmic staining of non-neuronal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

PDE2A (K-20) - sc-17228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE2A (K-20): sc-17228. Western blot analysis of PDE2A expression in mouse brain (A) and rat brain (B) tissue extracts.

PDE2A (A-17) - sc-31054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PDE2A (N-20) - sc-17227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE2A (N-20): sc-17227. Western blot analysis of PDE2A expression in mouse brain (A) and rat brain (B) tissue extracts.

PDE2A (V-18) - sc-31052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PDE2A antibody - ab125677 from Abcam

Prices $378.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PDE2A antibody (ab125677) at 1/2000 dilutionLane 1 : COS cells, non- transfectedLane 2 : COS cells, transfected with Human PDE1A3Lane 3 : COS cells transfected with Human PDE2A3Lane 4 : COS cells, transfected with Human PDE3ALane 5 : COS cells, transfected with Human PDE3BLane 6 : COS cells, transfected with Human PDE4D2Lane 7 : COS cells, transfected with Human PDE5A1Lane 8 : COS cells, transfected with Human PDE5A3Lane 9 : COS cells, transfected with Human PDE7A1Lane 10 : COS cells transfected with Human PDE8A1Lane 11 : COS cells, transfected with Human PDE10A1Lane 12 : COS cells, transfected with Human PDE11A1developed using the ECL technique

Anti-PDE2A antibody - ab14604 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE2A antibody - ab14605 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE2A antibody - ab55555 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PDE2A antibody [5D9] - ab117974 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5D9
All lanes : Anti-PDE2A antibody [5D9] (ab117974) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PDE2A Lysates/proteins at 5 µg per lane.

Anti-PDE2A antibody [EPR9688] - ab140650 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9688
All lanes : Anti-PDE2A antibody [EPR9688] (ab140650) at 1/1000 dilutionLane 1 : Fetal brain cell lysatesLane 2 : Fetal forebrain cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP conjugated goat anti-rabbit at 1/2000 dilution

Anti-PDE2A Antibody (C-Terminus) - LS-C82363 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of PDE2A antibody (1:2,000) against lysate from COS cells transfected with the indicated human PDE isoform.

Anti-PDE2A Antibody (N-Terminus) - LS-C135381 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDE2A antibody LS-C135381 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-PDE2A Antibody (clone 5D9) - LS-C172594 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5D9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A.

Anti-Pde2 / PDE2A Antibody (aa850-941, Azide-free) - LS-C328218 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-PDE2A Antibody (N-Terminus) IHC-plus™ - LS-A733 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PDE2A antibody LS-A733 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PDE2A Antibody (clone 4D2) - LS-C172596 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A.

Anti-PDE2A Antibody (clone 4F4) - LS-C197857 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F4
PDE2A monoclonal antibody (M01), clone 4F4 Western Blot analysis of PDE2A expression in IMR-32.

Anti-PDE2A Antibody (clone 2F1) - LS-C172597 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A.

Anti-PDE2A Antibody (clone 2A5) - LS-C172646 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A5
Anti-PDE2A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE2A.

Anti-PDE2A Antibody (clone 4H8) - LS-C172625 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4H8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE2A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE2A.

Anti-PDE2A Antibody (clone 1G9) - LS-C172624 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G9
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-PDE2A mouse monoclonal antibody.

Anti-PDE2A Antibody (clone 3A4) - LS-C172655 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A4
IHC of paraffin-embedded Human Kidney tissue using anti-PDE2A mouse monoclonal antibody.

Anti-PDE2A Antibody (clone 4D10) - LS-C172846 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D10
Anti-PDE2A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE2A.
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