Gene Symbol | PDE2A |
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Entrez Gene | 5138 |
Alt Symbol | CGS-PDE, PDE2A1, PED2A4, cGSPDE |
Species | Human |
Gene Type | protein-coding |
Description | phosphodiesterase 2A, cGMP-stimulated |
Other Description | cGMP-dependent 3',5'-cyclic phosphodiesterase|cGMP-stimulated phosphodiesterase 1|cGMP-stimulated phosphodiesterase 4|cyclic GMP-stimulated phosphodiesterase |
Swissprots | Q5J791 O00408 Q6ZMR1 E9PGI1 B3KRV5 Q5J793 B2R646 F6W5Z0 Q5J792 |
Accessions | CCQ43186 EAW74861 EAW74862 O00408 AI498038 AK092278 BAG52517 AK095024 BAG52972 AK131525 BAD18664 AK295676 BAG58533 AK312434 BAG35343 AY495087 AAS75513 AY495088 AAS75514 AY495089 AAS75515 BC040974 AAH40974 BI760519 DA219662 DA227593 DA243617 DA325165 DA329075 DA332549 DA504595 DA801834 DB068707 U67733 AAC51320 XM_005274040 XP_005274097 XM_011545096 XP_011543398 NM_001143839 NP_001137311 NM_001146209 NP_001139681 NM_001243784 NP_001230713 NM_002599 NP_002590 |
Function | Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. |
Subcellular Location | Isoform PDE2A1: Cytoplasm {ECO:0000269|PubMed:19632989}. |
Tissue Specificity | Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas. |
Top Pathways | Morphine addiction, cGMP-PKG signaling pathway, Purine metabolism |
Active human PDE2A full length protein - ab125613 from Abcam
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Active rat PDE2A full length protein - ab198484 from Abcam
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Human PDE2A protein fragment - ab114923 from Abcam
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PDE2A Antibody Blocking Peptide - LS-E20457 from LifeSpan Bioscience
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PDE2A Antibody Blocking Peptide - LS-E29255 from LifeSpan Bioscience
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Recombinant Human PDE2A Protein - H00005138-Q01 from Novus Biologicals
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Pde2a Blocking Peptide - 33R-1799 from Fitzgerald
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PDE2A - H00005138-Q01-10 from Acris Antibodies
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PDE2A - H00005138-Q01-25 from Acris Antibodies
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PDE2A Control Peptide - AP10205CP-N from Acris Antibodies
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PDE2A Control Peptide - AP10206CP-N from Acris Antibodies
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PDE2A (GST) Active Human Recombinant Protein - GWB-A3CBB9 from Genway Biotech
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PDE2A (FLAG), Active Human Recombinant Protein - GWB-568389 from Genway Biotech
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Recombinant Human PDE2A, GST-tagged, Active - PDE2A-472H from Creative Biomart
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Recombinant Human PDE2A , His tagged - PDE2A -906H from Creative Biomart
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Recombinant Human PDE2A - PDE2A-29979TH from Creative Biomart
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Recombinant Human PDE2A - PDE2A-606H from Creative Biomart
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Human PDE2A / CGS-PDE Protein (aa 215-900, His Tag) - 13031-H08B-20 from Sino Biological
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Recombinant Human cGMP-dependent 3',5'-cyclic phosphodiesterase(PDE2A) ,partial - CSB-YP517282HU CSB-EP517282HU CSB-BP517282HU CSB-MP517282HU from Cusabio
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cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A), partial, Recombinant Protein - MBS1226370 from MyBioSource
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Recombinant Human PDE2A / CGS-PDE Protein (aa 215-900, His tag) - PKSH030756 from Elabscience
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PDE2A Recombinant Protein Antigen - NBP2-48608PEP from Novus Biologicals
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PDE2A-Blocking-Peptide-C-Term - BP22001b from Abgent, a WuXi AppTec company
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PDE2A Peptide, Human - M34GP11500H from Creative Peptides
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Human PDE2A His tag (215-900) peptide - orb72174 from Biorbyt
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