PDE2A

Gene Symbol PDE2A
Entrez Gene 5138
Alt Symbol CGS-PDE, PDE2A1, PED2A4, cGSPDE
Species Human
Gene Type protein-coding
Description phosphodiesterase 2A, cGMP-stimulated
Other Description cGMP-dependent 3',5'-cyclic phosphodiesterase|cGMP-stimulated phosphodiesterase 1|cGMP-stimulated phosphodiesterase 4|cyclic GMP-stimulated phosphodiesterase
Swissprots Q5J791 O00408 Q6ZMR1 E9PGI1 B3KRV5 Q5J793 B2R646 F6W5Z0 Q5J792
Accessions CCQ43186 EAW74861 EAW74862 O00408 AI498038 AK092278 BAG52517 AK095024 BAG52972 AK131525 BAD18664 AK295676 BAG58533 AK312434 BAG35343 AY495087 AAS75513 AY495088 AAS75514 AY495089 AAS75515 BC040974 AAH40974 BI760519 DA219662 DA227593 DA243617 DA325165 DA329075 DA332549 DA504595 DA801834 DB068707 U67733 AAC51320 XM_005274040 XP_005274097 XM_011545096 XP_011543398 NM_001143839 NP_001137311 NM_001146209 NP_001139681 NM_001243784 NP_001230713 NM_002599 NP_002590
Function Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Subcellular Location Isoform PDE2A1: Cytoplasm {ECO:0000269|PubMed:19632989}.
Tissue Specificity Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
Top Pathways Morphine addiction, cGMP-PKG signaling pathway, Purine metabolism

Active human PDE2A full length protein - ab125613 from Abcam

Category Protein
Prices $302.00, $1,845.00
Sizes 5 µg, 100 µg
Source Baculovirus infected sf9 cells
Species Human
Sample Phosphodiesterase Assay showing the specific activity of ab125613 as 5750 nmol/mg/min.

Active rat PDE2A full length protein - ab198484 from Abcam

Category Protein
Prices $1,250.00
Sizes 5 µg
Source Baculovirus infected sf9 cells
Species Rat
Example of specific activity of ab198484

Human PDE2A protein fragment - ab114923 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114923 at approximately 35.64kDa. Stained with Coomassie Blue.

PDE2A Antibody Blocking Peptide - LS-E20457 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PDE2A Antibody Blocking Peptide - LS-E29255 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human PDE2A Protein - H00005138-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Pde2a Blocking Peptide - 33R-1799 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PDE2A - H00005138-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PDE2A - H00005138-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PDE2A Control Peptide - AP10205CP-N from Acris Antibodies

Category Peptide
Prices $235.00
Sizes 250 µg

PDE2A Control Peptide - AP10206CP-N from Acris Antibodies

Category Peptide
Prices $235.00
Sizes 100 µg

PDE2A (GST) Active Human Recombinant Protein - GWB-A3CBB9 from Genway Biotech

Category Protein
Prices $600.00
Sizes 5 µg
Species Human
PDE2A (GST) Active Human Recombinant Protein

PDE2A (FLAG), Active Human Recombinant Protein - GWB-568389 from Genway Biotech

Category Protein
Prices $600.00
Sizes 5 µg
Species Human
PDE2A (FLAG), Active Human Recombinant Protein

Recombinant Human PDE2A, GST-tagged, Active - PDE2A-472H from Creative Biomart

Category Protein
Source Sf9 insect cells using baculovirus.

Recombinant Human PDE2A , His tagged - PDE2A -906H from Creative Biomart

Category Protein
Source Baculovirus-Insect Cells
Species Human

Recombinant Human PDE2A - PDE2A-29979TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human PDE2A - PDE2A-606H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Human PDE2A / CGS-PDE Protein (aa 215-900, His Tag) - 13031-H08B-20 from Sino Biological

Category Protein
Prices $138.00, $298.00
Sizes 20 µg, 50 µg
Source Baculovirus-Insect Cells
Species Human

Recombinant Human cGMP-dependent 3',5'-cyclic phosphodiesterase(PDE2A) ,partial - CSB-YP517282HU CSB-EP517282HU CSB-BP517282HU CSB-MP517282HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A), partial, Recombinant Protein - MBS1226370 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human PDE2A / CGS-PDE Protein (aa 215-900, His tag) - PKSH030756 from Elabscience

Category Protein
Source Baculoviru
Species Human

PDE2A Recombinant Protein Antigen - NBP2-48608PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E. coli
Species Human

PDE2A-Blocking-Peptide-C-Term - BP22001b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PDE2A Peptide, Human - M34GP11500H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Human PDE2A His tag (215-900) peptide - orb72174 from Biorbyt

Category Peptide
Prices $417.00, $748.00
Sizes 20 μg, 50 μg
Source Insect
Species Human
SDS-PAGE analysis of human PDE2A His tag (215-900) peptide
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