ALDH4A1

Gene Symbol	ALDH4A1
Entrez Gene	8659
Alt Symbol	ALDH4, P5CD, P5CDh
Species	Human
Gene Type	protein-coding
Description	aldehyde dehydrogenase 4 family, member A1
Other Description	L-glutamate gamma-semialdehyde dehydrogenase|P5C dehydrogenase|aldehyde dehydrogenase family 4 member A1|delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial|mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase
Swissprots	Q16882 A8K1Q7 Q53HU4 Q96IF0 Q9UDI6 Q8IZ38 P30038 D2D4A3 Q5JNV6 B4DGE4
Accessions	EAW94858 EAW94859 EAW94860 P30038 AK222486 BAD96206 AK289972 BAF82661 AK294552 BAG57755 BC007581 AAH07581 BC023600 AAH23600 BM856369 BX649081 DC318624 DQ893505 ABM84431 DQ896489 ABM87488 FJ462711 ACN89883 U24266 AAC50500 U24267 AAC50501 XM_011542352 XP_011540654 XM_011542353 XP_011540655 XR_946786 NM_001161504 NP_001154976 NM_003748 NP_003739 NM_170726 NP_733844
Function	Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. {ECO:0000269|PubMed:22516612}.
Subcellular Location	Mitochondrion matrix.
Tissue Specificity	Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.
Top Pathways	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ALDH4 Lysate(Denatured) - H00008659-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ALDH4A1 Overexpression Lysate (Denatured) - H00008659-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ALDH4A1 (h2): 293T Lysate - sc-174976 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Human ALDH4A1 Insect Cell Lysate (WB positive control) - 12856-HNCBL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human ALDH4A1 Insect Cell Lysate (WB positive control) - 12856-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human ALDH4A1 Baculovirus-Insect Cells Transfected Lysate Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175174 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

ALDH4A1 Overexpression Lysate (Denatured) - H00008659-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Human ALDH4A1 Baculovirus-Insect Cells Transfected Lysate Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175269 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human ALDH4A1 Knockdown Stable Cell Line - CSC-DC000487 from Creative biogene Category Cell Line Species Human

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