ALDH4A1

Gene Symbol ALDH4A1
Entrez Gene 8659
Alt Symbol ALDH4, P5CD, P5CDh
Species Human
Gene Type protein-coding
Description aldehyde dehydrogenase 4 family, member A1
Other Description L-glutamate gamma-semialdehyde dehydrogenase|P5C dehydrogenase|aldehyde dehydrogenase family 4 member A1|delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial|mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase
Swissprots Q16882 A8K1Q7 Q53HU4 Q96IF0 Q9UDI6 Q8IZ38 P30038 D2D4A3 Q5JNV6 B4DGE4
Accessions EAW94858 EAW94859 EAW94860 P30038 AK222486 BAD96206 AK289972 BAF82661 AK294552 BAG57755 BC007581 AAH07581 BC023600 AAH23600 BM856369 BX649081 DC318624 DQ893505 ABM84431 DQ896489 ABM87488 FJ462711 ACN89883 U24266 AAC50500 U24267 AAC50501 XM_011542352 XP_011540654 XM_011542353 XP_011540655 XR_946786 NM_001161504 NP_001154976 NM_003748 NP_003739 NM_170726 NP_733844
Function Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. {ECO:0000269|PubMed:22516612}.
Subcellular Location Mitochondrion matrix.
Tissue Specificity Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.
Top Pathways Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism

ALDH4A1 CRISPR/Cas9 KO Plasmid (h) - sc-404676 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 HDR Plasmid (h) - sc-404676-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 Double Nickase Plasmid (h) - sc-404676-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 Double Nickase Plasmid (h2) - sc-404676-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 CRISPR Activation Plasmid (h) - sc-404676-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 CRISPR Activation Plasmid (h2) - sc-404676-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 Lentiviral Activation Particles (h) - sc-404676-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 Lentiviral Activation Particles (h2) - sc-404676-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALDH4A1 siRNA (h) - sc-72478 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALDH4A1 shRNA Plasmid (h) - sc-72478-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALDH4A1 shRNA (h) Lentiviral Particles - sc-72478-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALDH4A1 RNAi - H00008659-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ALDH4A1 RNAi - H00008659-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN3047 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3047 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09420 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09420

ALDH4A1 siRNA (Human) - CRH5694 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALDH4A1 - MBS8220559 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ALDH4A1 (NM_003748.3) - SHH234930 from Creative biogene

Category siRNA
Species Reactivities Human

Human ALDH4A1 siRNA - orb266196 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALDH4A1 shRNA Plasmid (Human) - CHH5694 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ALDH4A1 miRNA 3'UTR clone - MiUTR3H-08734 from Creative biogene

Species Reactivities Human

ALDH4A1 miRNA 3'UTR clone - MiUTR3H-08735 from Creative biogene

Species Reactivities Human

ALDH4A1 miRNA 3'UTR clone - MiUTR3H-08736 from Creative biogene

Species Reactivities Human
Search more